Results 291 to 300 of about 482,781 (345)

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

open access: yesPM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae   +4 more
wiley   +1 more source

Mers coronavirus infection of rabbits

open access: yesJournal of Comparative Pathology, 2015
Bart L. Haagmans   +13 more
openaire   +2 more sources

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho   +1 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Efficacy and safety of anifrolumab across organ domains of systemic lupus erythematosus: A systematic review and meta‐analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
A systematic review and meta‐analysis were conducted to review all clinical trial results of anifrolumab for treating systemic lupus erythematosus. Fourteen studies were included comprising 1322 patients and five studies were meta‐analyzed. It was found that anifrolumab 300 mg IV led to clinical improvement across composite lupus scores, cutaneous ...
Yomna W. Mahmoud   +11 more
wiley   +1 more source

All‐Aqueous Phase Segregation Integrated Electrochemical Aptamer Biosensor Enables Picomolar Detection of SARS‐CoV‐2 Spike Protein

open access: yesSmall, EarlyView.
A liquid‐liquid phase separation (LLPS) method is integrated into electrochemical aptamer biosensor (E‐AB) for improved sensitivity against SARS‐CoV‐2 spike protein. The LLPS successfully enriches spike protein prior to the E‐AB detection to achieve low picomolar limit of detection, applicable in synthetic human biofluids such as saliva and urine ...
Ryan Ho‐Ping Siu   +6 more
wiley   +1 more source

Emergency Medical Services Utilization during an Outbreak of Severe Acute Respiratory Syndrome (SARS) and the Incidence of SARS-associated Coronavirus Infection among Emergency Medical Technicians

open access: green, 2004
Patrick Chow‐In Ko   +8 more
openalex   +1 more source

Prospective Observational Study to Identify Factors Influencing Adverse Symptoms Associated With Endocrine Therapy in Breast Cancer Patients, a Protocol: Contribution of Japanese Traditional Medicine to Quality of Life and Work Productivity

open access: yesTraditional &Kampo Medicine, EarlyView.
ABSTRACT Aim Endocrine therapy causes side effects (SEs) such as hot flushes, joint stiffness, and psychological disorders in patients with breast cancer (BC). To address these symptoms, Japanese traditional (Kampo) medicine will be used as treatment.
Shin Takayama   +13 more
wiley   +1 more source

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