Results 31 to 40 of about 77,457 (174)
Coronaviruses of humans were first identified more than 60 years ago from individuals with respiratory infections, mainly mild. Two different viruses, 229E and OC43 were initially recognized. Because of difficulty in isolating them using standard techniques, many of the early studies of their occurrence were seroepidemiologic. They were confirmed to be
Monto, Arnold S. +2 more
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Vaccine Candidate Against COVID-19 Based on Structurally Modified Plant Virus as an Adjuvant
A recombinant vaccine candidate has been developed based on the major coronaviruses’ antigen (S protein) fragments and a novel adjuvant—spherical particles (SPs) formed during tobacco mosaic virus thermal remodeling.
Angelina O. Kovalenko +10 more
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We reviewed the timeline of key policies for control of the coronavirus disease epidemic and determined their impact on the epidemic and hospital burden in South Korea. Using a discrete stochastic transmission model, we estimated that multilevel policies,
Hae-Young Kim +13 more
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Corona viruses belong to a group of not yet well known viruses isolated in patients with infections of the upper respiratory organs, especially in winter months. It is presumed that they provoke about 15% - 20% of all infections. However, in the last years more attention has been paid to the role of human corona viruses in the provocation of sickness ...
N, Kuljić-Kapulica, A, Budisin
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Pooled nucleic acid amplification tests for severe acute respiratory syndrome coronavirus 2 could increase availability of testing at decreased cost.
Hannah Wang +10 more
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Structural Basis of MERS‐CoV Receptor Interactions and Antibody Neutralisations [PDF]
ABSTRACT Increasing outbreaks of coronaviruses underscore the importance of antivirals and vaccines that can combat a wide range of coronaviruses. Neutralising antibodies (nAbs), along with vaccines and small‐molecule drugs, are among the most promising treatments and prevention options against coronaviruses.
Gavor E +5 more
europepmc +2 more sources
Abstract This chapter begins by describing older coronaviruses, such as SARS and MERS, followed by the novel coronavirus SARS-CoV-2. Details of Pfizer’s mRNA vaccine are described and viral vector vaccines are also reviewed. This chapter will also discuss two small-molecule antiviral drugs: Gilead’s remdesivir and dexamethasone.
Schoeman, Dewald +2 more
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Back to the Future: Immune Protection or Enhancement of Future Coronaviruses
Before the emergence of SARS-CoV-1, MERS-CoV, and most recently, SARS-CoV-2, four other coronaviruses (the alpha coronaviruses NL63 and 229E and the beta coronaviruses OC43 and HKU1) had already been circulating in the human population. These circulating
Merit Bartels +3 more
doaj +1 more source
Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal.
Christine Haake +3 more
doaj +1 more source
Antiviral functionalization of cellulose using tannic acid and tannin-rich extracts
Due to seasonally appearing viruses and several outbreaks and present pandemic, we are surrounded by viruses in our everyday life. In order to reduce viral transmission, functionalized surfaces that inactivate viruses are in large demand.
Marjo Haapakoski +9 more
doaj +1 more source

