Results 81 to 90 of about 345,986 (348)

India's Bond Market-Developments and Challenges Ahead [PDF]

open access: yes
While India boasts a world-class equity market and increasingly important bank assets, its bond market has not kept up. The government bond market remains illiquid.
Schou-Zibell, Lotte, Wells, Stephen
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

THE MANAGEMENT OF FLOTATION IN CORPORATIVE DEBENTURE EXPENSE

open access: yesResearch on Enterprise in Modern Economy Theory and Practice, 2017
The capital market is one of many sites that allows raising capital by companies. One of the instruments in the capital market are corporate bonds. The purpose of this article is to analyze methods of cost management issue bonds on the Catalyst market ...
Katarzyna Kocoń
doaj   +1 more source

The Demand for Treasury Debt [PDF]

open access: yes
We show that the US Debt/GDP ratio is negatively correlated with the spread between corporate bond yields and Treasury bond yields. The result holds even when controlling for the default risk on corporate bonds.
Annette Vissing-Jorgensen   +1 more
core  

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Do significant risk warnings in annual reports increase corporate bond credit spreads? Evidence from China

open access: yesChina Journal of Accounting Research, 2019
Based on listed companies issuing bonds on the Shanghai and Shenzhen Stock Exchanges from 2007 to 2017, this study analyzes the relationship between significant risk warnings in Chinese companies’ annual reports and corporate bond credit spreads.
Xi Gao, Xiongyuan Wang, Furong Tian
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Formulation of a Dynamic Portfolio With Stocks and Fixed-income Instruments in the Indonesian Capital Market

open access: yesOrganizations and Markets in Emerging Economies, 2019
This research creates a crossed asset portfolio formulation dynamically with stocks and fixed-income instruments. This dynamic portfolio formulation did not require normally distributed data and accommodated the correlation among class assets which kept ...
Robiyanto Robiyanto   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy