Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
CORPORATE CULTURE AND ITS ROLE IN TALENTS' MANAGEMENT
The choice of 'getting' talent - to bring them up in-house or attract from outside - is closely connected with corporate culture. The article describes organizational (corporate) culture as a sphere of displaying spiritual and material life of the team ...
Sergey A. Kartashov +2 more
doaj +1 more source
COVID-19 Outbreak and Financial Performance of Chinese Listed Firms: Evidence From Corporate Culture and Corporate Social Responsibility. [PDF]
Sun Y, Li Y.
europepmc +1 more source
THE LINK BETWEEN ORGANIZATIONAL CULTURE AND CORPORATE PERFORMANCE - AN OVERVIEW [PDF]
The object of this paper is to examine organizational culture and organizational performance through an analysis of the existent culture models and the empirical studies conducted to examine the corporate culture and organizational performance link. Even
Corina Gavrea, Liviu Ilies
core
The phenomen of corporate culture of personality in the context of educology knowledges [PDF]
У статті розкрито сутність феномену «корпоративна культура особистості» з точки зору філософії, педагогіки, психології, менеджменту управління. Визначено структурні елементи та функції корпоративної культури особистості.
Бровко, Катерина Андріївна
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Relationship between Ethical Culture and Unethical Behavior in Work Groups: Testing the Corporate Ethical Virtues Model [PDF]
The Corporate Ethical Virtues Model, which is a model for measuring the ethical culture of organizations, has not been tested on its predictive validity. This study tests the relationship between this model and observed unethical behavior in work groups.
Kaptein, S.P.
core +1 more source
Budaya Perusahaan Dan Persepsi Pengembangan Karir Pada Karyawan Yang Bekerja Di PT. Telekomunikasi Indonesia [PDF]
The purpose of this study is to investigate the relationship between Corporate Culture and Perception of Carrier Development. The study was a field research which data collected through Scale of Corporate Culture and Scale of Perception of Carrier ...
Melinda, T. (Tina) +1 more
core
Generational Differences in the Perception of Corporate Culture in European Transport Enterprises
The workforce of an enterprise consists of employees of various ages with different personality types. Members of each generation differ not only in their behaviour, but also in their attitudes and opinions.
R. Kampf +3 more
semanticscholar +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

