Results 121 to 130 of about 731,657 (339)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

THE ROLE OF CORPORATE GOVERNANCE IN TRANSITION ECONOMIES: CONTRIBUTION AND DEVELOPMENT [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2016
With more evident process of globalization of the world market, the concept of corporate governance gains importance. The global economic crisis highlighted the problems of corporate governance both in developed countries and developing economies ...
OLIVERA GJORGIEVA-TRAJKOVSKA, KRUME NIKOLOSKI, BLAGICA KOLEVA , VESNA GEORGIEVA SVRTINOV   +3 more
doaj  

Critical Analysis of the Code of Corporate Governance in the Light of Islamic Principles of Corporate Governance

Pakistan Journal of Islamic Research, 2021
Corporate governance is intended to create accountability in companies in order to avoid corporate disasters, as it believes on prevention rather than cure.
Samza Fatima, Muhammad Bilal, Faiz Bakhsh Malik   +2 more
doaj  

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

Molecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch, Sara Sánchez‐Serra, Marta Rosàs‐Lapeña, Nicolás Costa‐Fraga, Judit Besalú‐Velázquez, Janet Illa‐Bernadí, Silvia Mateo‐Lozano, Florencia Cidre‐Aranaz, Thomas G.P. Grünewald, Ángel Díaz‐Lagares, Roser Lopez‐Alemany, Òscar M. Tirado   +11 more
wiley   +1 more source

Relationship between Corporate Governance, Corporate Sustainability and Financial Performance [PDF]

Pakistan Journal of Commerce and Social Sciences, 2019
This study aims to investigate three crucial questions. First, whether the corporate governance and corporate sustainability leads to improved firm financial performance or not?
Asma Munir , Farman Ullah Khan , Muhammad Usman, Sobia Khuram   +3 more
doaj  

The Second Amendment and Cyber Weapons - The Constitutional Relevance of Digital Gun Rights [PDF]

arXiv, 2018
In the future, the United States government can seek to limit the ownership and usage of cyber weapons. The question is whether the Second Amendment to the United States Constitution gives a right to bear and own military-grade cyber weapons, and if so, under which conditions. The framers of the Bill of Rights, ratified in 1791, did not limit the right
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, Volume 19, Issue 5, Page 1404-1421, May 2025.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Who Decides: Judges or Experts? Loper Bright, the End of Chevron and Its Impact on Corporate Governance [PDF]

In Loper Bright Enterprises v. Raimondo, 603 U.S. _____ (2024), the Supreme Court overruled the doctrine of Chevron deference, which had previously required courts to defer to reasonable agency guidance instead of reviewing rules and regulations de novo.
Heyman Center on Corporate Governance,
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Legal routes for accomplishing corporate environmental compliance against the "carbon peaking and carbon neutrality" goals [PDF]

arXiv
Against the macro-background of "carbon peaking and carbon neutrality" goals, eco-environment protection regulations are increasingly stricter. Facing high government regulatory risks and frequent environment lawsuits, corporate environmental compliance starts to play a vital role in healthy corporate operation.
arxiv