Results 81 to 90 of about 725,595 (337)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Corporate Governance: An Assessment

open access: yesOxford Review of Economic Policy, 2005
Corporate governance is one of the most topical and controversial areas of business and finance. This article provides an overview of the questions that it raises and proposed policy responses. It points to the diversity in systems of corporate governance around the world, the apparently paradoxical performance of different systems and an association ...
Becht, Marco   +2 more
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Analysis corporate governance in the Republic of Srpska [PDF]

open access: yesEkonomski Pogledi, 2013
Corporate governance is a concept whose implementation improves market position, attract domestic and foreign investors, capital markets and develops economies. Base of improving corporate governance is to define and implement the principles of corporate
Ševkušić Ljubiša
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

The influence of corporate governance international models on the development of accounting practice

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2019
The essence of the concept of «corporate governance model» has been considered. The main characteristics of international models of corporate governance have been analyzed.
V.Yu. Tsaruk
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Rationality, traditionalism and the state of corporate governance mechanisms: illustrations from a less developed country [PDF]

open access: yes, 2008
Purpose ? The purpose of this research is to provide an account of corporate governance practices in Bangladesh. This paper demonstrates that the traditionalist culture mediates the rationalist/legalist framework of corporate governance in Bangladesh ...
Choudhury, J, Uddin, S
core  

Corporate Governance [PDF]

open access: yes, 2017
This chapter considers corporate governance and control at the board level, a perspective little addressed in the critical theory informed accounting research literature and in the accounting research literature generally. With some exceptions, financial accounting, management accounting, auditing and social-environmental accounting literatures have ...
openaire   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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