Results 41 to 50 of about 4,887 (254)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Corporate Governance – The Importance of Communication and Culture

open access: yesIndian Journal of Science and Technology, 2016
Objectives: The purposefulness of the paper is to examine the significance of independence in corporate governance, issues and challenges that independent directors have to face and the importance of culture and communication. Analysis and Findings: The paper investigates how a firm’s governance maps between corporate governance and independent ...
B. Nalina, N. Panchanatham
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evolutionary characteristics of corporate environmental governance policies in China: a policy instrument analysis (1982–2023)

open access: yesFrontiers in Environmental Science
Corporate environmental governance has emerged as a critical global priority amid escalating environmental challenges. In recent years, many countries have implemented laws such as “Supply Chain Laws” and “Corporate Due Diligence Laws” to strengthen ...
Zehua Tian, Wusong Yang, Xi Tang
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Reform of Corporate Governance in the EU. CEPS Policy Brief No. 38, October 2003 [PDF]

open access: yes, 2003
[From the Introduction]. This paper analyses the European corporate governance debate and examines both the report entitled A Modern Regulatory Framework for Company Law in Europe prepared by the High Level Group of Company Law Experts (2002a ...
Lannoo, Karel, Khachaturyan, Arman.
core  

The Impact of Corporate Governance Mechanisms on Impression Management in Top 40 JSE-Listed Companies

open access: yesInternational Journal of Applied Research in Business and Management
Impression management in corporate reporting, which can obscure a firm’s financial position, has prompted increased focus on corporate governance mechanisms to enhance transparency and accountability.
Mziwendoda Cyprian Madwe   +2 more
doaj   +1 more source

Transparency of Accounting Information in Achieving Good Corporate Governance. True View and Fair Value [PDF]

open access: yesSocial Sciences and Education Research Review, 2016
One of the key factors affecting the efficient use of resources, the increase of shareholders confidence in the managers of the company, the success in achieving objectives and economic efficiency is the system of corporate governance by which a company ...
Mariana Man, Maria Ciurea
doaj  

Does corporate governance moderate the relationship between internal control system effectiveness and SMEs financial performance in Ghana?

open access: yesCogent Business & Management, 2022
The study examined the effect of the major component of an internal control system according to the COSO framework on the financial performance of SMEs registered with the Association of Ghana Industries (AGI) in Ghana.
Alhassan Musah   +4 more
doaj   +1 more source

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