Results 61 to 70 of about 23,539,740 (236)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Information security strategy in telemedicine and e-health systems: A case study of England’s shared electronic health record system [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 9/11/2010.Shared electronic health record (EHR) systems constitute an important Telemedicine and e-Health application. Successful implementation of shared
Mohammad, Yara Mahmoud
core +5 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Study on the Support Systems for Corporate Governance [PDF]
The problems generated by the information asymmetry within the agency relationships at corporation level, governments and capital markets led to a higher necessity for corporate governance (CG).
Claudiu BRANDAS
doaj
MULTIAGENT APPROACH FOR MANAGING THE INFORMATION SPACE OF CORPORATE SYSTEMS
The subject matter of the study is the integration and management of information resources of distributed computing corporate systems within the common information space.
Valentin Filatov, Valerii Semenets
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Study of Multi-Service Networks and Communication Systems Using Distributed Network Technology in Mountain Areas [PDF]
It should be noted that the development of the digital economy directly depends on the introduction of advanced technologies: nanotechnology, biotechnology, complex energy systems technologies, quantum technologies, etc. At the same time, it is difficult
Rustamova D. F. +4 more
doaj +1 more source
Information systems reference guide
"Revised August 1989."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the ...
core
application/pdf; "July 2009.""The Division of Information Systems and Communications, also known as DISC, is a fee-based organization comprised of seven operational units that deliver 24 x 7 central information technology services such as statewide data,
Kansas. Department of Administration. Division of Information Systems and Communications.
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

