Results 131 to 140 of about 60,898 (347)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Talking bodies: Sexual abuse, language, illness and dissociation in Camilla Gibb's mouthing the words [PDF]
, 2018 Abdel-Rahman Téllez, Shadia
core +2 more sources
Writing biology with mutant mice: the monstrous potential of post genomic life [PDF]
, 2011 Social scientific accounts identified in the biological grammars of early genomics a monstrous reductionism, ‘an example of brute life, the minimalist essence of things’ (Rabinow, 1996, p. 89).
Davies, GF
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
ТЕОРЕТИЧЕСКИЕ ПОДХОДЫ К ПРЕДСТАВЛЕНИЮ О ТЕЛЕСНОСТИ У СОВРЕМЕННОЙ МОЛОДЕЖИ
Cifra: ПсихологияСтатья посвящена феномену телесности как одной из ключевой тем в современной мире и психологии. В данной статье рассматривается понятие телесность с позиции разных авторов и подходов.
Юрченко Е.В.
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Haptic vision, footwork, place-making: A peripatetic phenomenology of the mobile phone pedestrian [PDF]
, 2009 In this paper we aim to develop a post-phenomenology of walking through an analysis of the relation between pedestrian mobility and the use of mobile devices, and then apply this analysis to users of third and fourth generation location-aware touch ...
Richardson, I., Wilken, R.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
“He Has Music in Him”: Musical Moments, Dance and Corporeality in Joker (2019)
Alphaville: Journal of Film and Screen MediaDanijela Kulezic-Wilson has discussed at length how the use of music in cinema adds to its corporeality and both fleshes out and gives life to otherwise spectral images.
Jessica Shine
doaj +1 more source