Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Purpose To evaluate how Large Language Models (LLMs) align with a concurrently performed human medical expert‐modified Delphi study on the posterolateral corner and to qualitatively analyze LLM behavior. Methods Four commercially available and current LLMs (Gemini‐2.5‐Pro. GPT‐4o, o4‐mini, and o3) were tasked with rating posterolateral corner consensus
Yinan Yu +6 more
wiley +1 more source
BanglaHateCorpus: A large-scale bangla benchmark for hate speech classification and a transformer-based deep learning method. [PDF]
Rodela AT +4 more
europepmc +1 more source
Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman +1 more
wiley +1 more source
Across established non-invasive neuromodulation and emerging deep-targeting strategies: a comparative bibliometric analysis of TI, TMS, tDCS, and tFUS/TUS/LIFU. [PDF]
Wang G, Wu S.
europepmc +1 more source
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan +7 more
wiley +1 more source
SpartanAnatomy.org: Evaluating a new interactive neuroradiology tool for early medical education
Abstract Teaching neuroanatomy through the lens of magnetic resonance imaging (MRI) offers medical students a strong foundation for success. However, many existing MRI learning resources lack interactivity and user‐friendliness, require payment, or include an overwhelming number of labeled structures.
Halie Kerver +3 more
wiley +1 more source
Brain Health Research in PubMed/MEDLINE: A Bibliometric Analysis of Thematic Structure and Health-Economic Terminology with a Conceptual Performance-Management Framework. [PDF]
Lampropoulos IC, Xiromerisiou G.
europepmc +1 more source

