Results 121 to 130 of about 24,257,809 (325)
Advanced Science, EarlyView.Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Advanced Science, EarlyView.Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol +17 more
wiley +1 more source
Word recognition from tiered phonological models [PDF]
, 1994 Phonologically constrained morphological analysis (PCMA) is the decomposition of words into their component morphemes conditioned by both orthography and pronunciation. This article describes PCMA and its application in large-vocabulary continuous speech
Huckvale, M
core
Advanced Science, EarlyView.This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen +7 more
wiley +1 more source
Clitic doubling in Peninsular and Rioplatense Spanish: a comparative corpus investigation
Isogloss, 2020 The current study compares the distribution of clitic doubling (CD) in two varieties of Spanish: Peninsular Spanish and Rioplatense Spanish. Based on two corpora of colloquial speech we investigate under which conditions CD with pronominal and nominal ...
Esther Rinke +2 more
doaj
Corpus Analysis in Philosophy [PDF]
, 2016 The experimental philosophy movement advocates the use of empirical methods in philosophy. The methods most often discussed and in fact employed in experimental philosophy are appropriated from the experimental paradigm in psychology.
Bluhm, Roland
core
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
Advanced Science, EarlyView.We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source
A doublet pair drop and dribble [PDF]
Sinteze, 2019 The paper deals with the content relations of the nouns drop and dribble in order to see whether they are equal or point to each other, more precisely, the possible duplicity or synonymity of this pair is examined.
Bacić Cica Z.
doaj
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source