Results 31 to 40 of about 78,121 (262)

Morphometric changes of the corpus callosum in congenital blindness. [PDF]

PLoS ONE, 2014
We examined the effects of visual deprivation at birth on the development of the corpus callosum in a large group of congenitally blind individuals. We acquired high-resolution T1-weighted MRI scans in 28 congenitally blind and 28 normal sighted subjects
Francesco Tomaiuolo, Serena Campana, D Louis Collins, Vladimir S Fonov, Emiliano Ricciardi, Giuseppe Sartori, Pietro Pietrini, Ron Kupers, Maurice Ptito   +8 more
doaj   +1 more source

Delusional Disorder in a Patient with Corpus Callosum Agenesis [PDF]

Journal of Clinical and Diagnostic Research, 2016
Agenesis of corpus callosum is rare and associated neuropsychiatric abnormalities reported are epilepsy, Asperger's syndrome, learning problems, depression, schizophrenia, conduct disorder and conversion symptoms.
M.S. BHATIA, RASHMITA SAHA, NIMISHA DOVAL   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Isthmus of the corpus callosum – An anatomical investigation

Translational Research in Anatomy
Introduction: The corpus callosum, a principal commissural fibre-bundle of the brain, connects the two cerebral hemispheres, facilitating interhemispheric communication, cognitive and emotional processes.
Yukta Maharajh, René Human-Baron, Gerda Venter   +2 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

DTI study of corpus callosum in schizophrenia patients with different treatment response

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To compare the white matter fiber integrity of corpus callosum in schizophrenia patients with different treatment response with normal controls.
SHI Xiao⁃meng, HUANG Jia⁃shuang , GAO Shu⁃zhan , ZHANG Dao⁃qiang, XU Xi⁃jia   +4 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Elevated Corpus Callosum T1rho Reflects Disease Burden and Structural Atrophy in Multiple Sclerosis

Diagnostics
Background/Objectives: Corpus callosum atrophy is a well recognized feature of multiple sclerosis (MS), which has been associated with disease duration and severity.
Lei Wang, Tiffany Y. So, Ziqiang Yu, Weitian Chen, Joseph C. H. Choi, Qiyong H. Ai, Queenie Chan, Alexander Y. L. Lau   +7 more
doaj   +1 more source

Corpus Callosum Agenesis and Schizophrenia: A Case Report [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2006
Partial or complete agenesis of the corpus callosum is a rare developmental anomaly of unknown cause. Corpus callosum plays an integrative role in the transmission of sensitive, motor and cognitive information coming from the homologous areas of the ...
Ahmet Kocabıyık, Hatice Alibaşoğlu, Nesrin Tomruk, Nihat Alpay   +3 more
doaj  

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source