Introduction: The autologous skin flap is still the mainstream method for penile reconstruction, but it is very difficult to reconstruct a functional corpus cavernosum. Tissue engineering provides a new idea aiming to restore the damaged or absent corpus
Zilong Cao, MD +6 more
doaj +1 more source
Morphological and molecular analysis of apoptosis in the corpus cavernosum of rats submitted to a chronic alcoholism model [PDF]
Purpose To evaluate the effect of chronic alcoholism on morphometry and apoptosis mechanism and correlate with miRNA-21 expression in the corpus cavernosum of rats.
Rogério José de Azevedo Meirelles +14 more
doaj +1 more source
Penile reconstruction using mesenchymal stem cells [PDF]
PURPOSE: To compare the reconstruction of corpus cavernosum segments when seeded with mesenchymal stem cells and when stem cells are infused intravenously.METHODS: Sixteen New Zealand rabbits were submitted to reconstruction of the corpus cavernosum and ...
Marcus Laks +4 more
doaj +1 more source
Endogenous urotensin II selectively modulates erectile function through eNOS. [PDF]
BACKGROUND:Urotensin II (U-II) is a cyclic peptide originally isolated from the neurosecretory system of the teleost fish and subsequently found in other species, including man.
Roberta d'Emmanuele di Villa Bianca +9 more
doaj +1 more source
Modifications of erectile tissue components in the penis during the fetal period. [PDF]
The penile erectile tissue has a complex microscopic anatomy with important functions in the mechanism of penile erection. The knowledge of such structures is necessary for understanding the normal physiology of the adult penis.
Carla B M Gallo +4 more
doaj +1 more source
Single-cell transcriptome atlas of the human corpus cavernosum
The corpus cavernosum is the most important structure for penile erection, and its dysfunction causes physiological and psychological problems. Here the authors perform single-cell RNA-sequencing on corpus cavernosum samples from males with normal ...
LiangYu Zhao +21 more
doaj +1 more source
Impaired Corpus Cavernosum Relaxation Is Accompanied by Increased Oxidative Stress and Up-Regulation of the Rho-Kinase Pathway in Diabetic (Db/Db) Mice. [PDF]
Basal release of nitric oxide from endothelial cells modulates contractile activity in the corpus cavernosum via inhibition of the RhoA/Rho-kinase signaling pathway.
Fernanda B M Priviero +5 more
doaj +1 more source
Expression profiles of eNOS, iNOS and microRNA-27b in the corpus cavernosum of rats submitted to chronic alcoholism and Diabetes mellitus [PDF]
Purpose: To evaluate the expression of endothelial and inducible NOS in addition to the miRNA-27b in the corpus cavernosum and peripheral blood of healthy rats, diabetic rats, alcoholic rats and rats with both pathologies.
Joao Paulo da Cunha +8 more
doaj +2 more sources
Case Presentation: We describe a case of spontaneous partial segmental thrombosis of the corpus cavernosum (PSTCC). Discussion: PSTCC is a rare condition in which thrombus formation occurs in the corpus cavernosum.
Jesse Wray +4 more
doaj +1 more source
Surgical Management of Idiopathic Partial Thrombosis of the Corpus Cavernosum
A 36-year-old African American man presented to the emergency department with 2 days of left-sided perineal pain after sexual activity. He was found to have induration in the left perineum overlying the proximal left corporal body.
Danish Singh, BS +4 more
doaj +1 more source

