Results 51 to 60 of about 970,758 (130)

Nocturnal awakening secondary to pain in sleep‐related painful erection: A case report and literature review

Sleep Research, Volume 3, Issue 3, Page 286-291, September 2026.
Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang, Jinxiang Cheng, Jiaxiu He, Rui Guo, Changjun Su, Xianchao Zhao   +5 more
wiley   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

UroPrecision, Volume 4, Issue 3, Page 189-193, September 2026.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega, Mariela R. Martinez, Steven Friedman, Tehilla Adams, Jordan L. Mendelson, William Nguyen, Jordan S. Gitlin   +6 more
wiley   +1 more source

Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling

Andrology, Volume 14, Issue 6, Page 1831-1846, September 2026.
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu, Peng Hu, Zizhong Yang, Zhenghui Jin, Xiaoyu Zhu, Tao Wang, Jihong Liu, Kai Cui   +7 more
wiley   +1 more source

Relaxant effects of some benzothiazolinone derivatives on isolated rabbit corpus cavernosum

, 2001
In the present study, two 6-(fluorobenzoyl)-3-piperazinomethyl-2benzothiazoline ne derivatives were synthesized and their relaxant effects on isolated rabbit corpus cavernosum investigated.
Simek, R, Gokce, G, Sarioglu, Y, Ayan, S, Yildirim, ŞAHİN, Safak, C, Gokce, GÖKHAN, Yildirim, S   +7 more
core   +3 more sources

Use of Sildenafil Citrate for the Treatment of Erectile Dysfunction in Stallions: First Case Reports

Reproduction in Domestic Animals, Volume 61, Issue 9, September 2026.
ABSTRACT Pharmacological aids can be useful alternatives to enhance penile erection and/or improve ejaculatory function, thereby prolonging the reproductive life of stallions with ejaculatory disorders. This study aimed to evaluate the effects of sildenafil citrate in the treatment of erectile dysfunction and on semen quality in two aged stallions, a ...
Thaís Mendes Sanches Cavalero, Frederico Ozanam Papa, Gabriel Augusto Monteiro, Patrícia de Mello Papa, Felipe Pires Hartwig, Camila de Paula Freitas‐Dell'Aqua, Marco Antônio Alvarenga, Marcela Souza e Freitas, Yame Fabres Robaina Sancler‐Silva   +8 more
wiley   +1 more source

The hypoactive corpora cavernosa with degenerative erectile dysfunction: a new syndrome

BMC Urology, 2006
Background In a group of 22 patients with erectile dysfunction, vasculogenic, neurogenic, endocrinologic or psychogenic investigations failed to find a cause for their erectile dysfunction.
El Sibai Olfat, Ahmed Ismail, Shafik Ahmed, Shafik Ali A   +3 more
doaj   +1 more source

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions of TPN171, a Novel Phosphodiesterase Type 5 Inhibitor

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT TPN171 is a potent phosphodiesterase type 5 inhibitor used to treat pulmonary arterial hypertension and erectile dysfunction, primarily metabolized by CYP3A4. This study aimed to evaluate its drug–drug interaction (DDI) potential and determine the optimal dosing when co‐administered with CYP3A4 modulators.
Guanghui Tian, Tao Chen, Lei Li, Zhiqiang Wang, Hao Yang, Jiaxiang Juan, Yuanqin Duan, Jianghong Pei, Jingying Jia   +8 more
wiley   +1 more source

Leiomyoma of the Corpus Cavernosum of the Penis

, 2008
While soft tissue tumors can occur in the penis, corpus cavernous tumors are rare. Reported cases of corpus cavernous tumors are from metastases of advanced malignancy, such as cancers of the bladder, prostate, rectosigmoid colon, kidney, pancreas, liver,
劉詩斌;孫家棟;張尚仁;陳淳;謝汝敦, LIU, SHIH-PING;SHUN, CHIA-TUNG;CHANG, SHANG-JEN;CHEN, JUN;HSIEH, JU-TON   +1 more
core  

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, Volume 183, Issue 15, Page 4091-4110, August 2026.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira, Edson Antunes, Fabiola Zakia Monica, Gilberto De Nucci   +3 more
wiley   +1 more source

IL-17A exacerbates corpus cavernosum fibrosis and neurogenic erectile dysfunction by inducing CSMC senescence via the mTORC2-ACACA pathway

BMC Medicine
Background Neurogenic erectile dysfunction, characterized by neurological repair disorders and progressive corpus cavernosum fibrosis (CCF), is an unbearable disease with limited treatment success.
Wende Yang, Jiafeng Fang, Jiancheng Zhai, Chen Qiu, Zhenkang Liang, Qianhui Liu, Hongbo Wei   +6 more
doaj   +1 more source