EARLY LIFE EXPOSURE TO GENISTEIN AND DAIDZEIN DISRUPTS STRUCTURAL DEVELOPMENT OF REPRODUCTIVE ORGANS IN FEMALE MICE [PDF]
, 2012 In mice, exposure to isoflavones (ISO), abundant in soy infant formula, during the first 5 d of life alters structural and functional development of reproductive organs. Effects of longer exposures are unknown.
Chen, Jianmin +2 more
core +2 more sources
Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
iMetaMed, EarlyView.As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source
Phosphatidylinositol 3-kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities. [PDF]
, 2019 BackgroundThe phosphatidylinositol 3-kinase (PI3K) pathway is frequently altered in cancer. This report describes the landscape of PI3K alterations in solid tumors as well as co-alterations serving as potential resistance/attenuation mechanisms ...
Albacker, Lee +6 more
core +1 more source
An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract
Journal of Applied Toxicology, EarlyView.ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston +2 more
wiley +1 more source
Journal of Clinical Ultrasound, EarlyView.In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li +3 more
wiley +1 more source
Global incidence and mortality trends of corpus uteri cancer and associations with gross domestic product, human development index, lifestyle, and metabolic risk factors [PDF]
, 2023 Junjie Huang +10 more
openalex +1 more source
Journal of Ultrasound in Medicine, EarlyView.Objective To correlate the sonographic severity of adenomyosis, assessed with real‐time ultrasound and a novel semi‐quantified method (XI‐VOCAL counting and categories) with adenomyosis‐associated symptoms. Methods This observational study was conducted in a tertiary referral outpatient clinic.
Lisa M. Trommelen +5 more
wiley +1 more source
PLoS ONE, 2018 BackgroundLocal anesthetics (LAs) are increasingly used as therapeutics due to their multiple molecular effects. They may be potential agents also in gynecology and reproductive medicine.
Fabian Weinschenk +5 more
doaj +1 more source
Role of magnetic resonance imaging in the diagnosis of recurrent cancer of the cervix uteri
Опухоли женской репродуктивной системы, 2014 Objective: to define a role of magnetic resonance imaging (MRI) in the follow-up of patients with cancer of the cervix uteri (CCU), who have undergone radiation therapy and chemoradiation therapy and to describe the types of the MRI pattern of recurrent ...
Z. N. Shavladze +4 more
doaj +1 more source
Risk and Prognosis of Second Corpus Uteri Cancer after Radiation Therapy for Pelvic Cancer: A Population-Based Analysis [PDF]
, 2022 Guanhua Yu +8 more
openalex +1 more source