Results 61 to 70 of about 436,306 (291)

Risk of critical illness among patients with solid cancers: a population-based observational study of 118,541 adults [PDF]

, 2015
Importance: Critical illness may be a potential determinant of cancer outcomes and geographic variations, but its role has not been described before. Objective: To determine the incidence of admission to intensive care units (ICUs) within 2 years ...
Kinsella, John, McLoone, Philip, Morrison, David S., Puxty, Kathryn, Quasim, Tara, Sloan, Billy   +5 more
core   +1 more source

HISTOPATHOLOGICAL AND HORMONAL EFFECTS OF DIFFERENT DOSES OF ASPIRIN ON THE FEMALE REPRODUCTIVE SYSTEM OF ALBINO RATS [PDF]

Basrah Journal of Veterinary Research, 2016
The present study was carried out to investigate the effect of aspirin on the female reproductive organs in albino rats. (21) mature female albino rats (150-170gm) were divided into three groups: 1st group which treated as negative control group, it was ...
Khalil G. Chelab, Zainab I. Mohammed, SH. Ali   +2 more
doaj   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

Advanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau, Monica A. Rionda, Evelyn Cho, Jamison G. Clark, Robin E. Kruger, Ruth K. Chan‐Sui, Vasantha Padmanabhan, Molly B. Moravek, Ariella Shikanov   +8 more
wiley   +1 more source

Associations of genetic susceptibility to 16 cancers with risk of breast cancer overall and by intrinsic subtypes

HGG Advances, 2022
Summary: Certain genetic variants are associated with risks of multiple cancers. We investigated breast cancer risk with overall genetic susceptibility to each of 16 other cancers.
Jungyoon Choi, Guochong Jia, Wanqing Wen, Ran Tao, Jirong Long, Xiao-Ou Shu, Wei Zheng   +6 more
doaj   +1 more source

EARLY LIFE EXPOSURE TO GENISTEIN AND DAIDZEIN DISRUPTS STRUCTURAL DEVELOPMENT OF REPRODUCTIVE ORGANS IN FEMALE MICE [PDF]

, 2012
In mice, exposure to isoflavones (ISO), abundant in soy infant formula, during the first 5 d of life alters structural and functional development of reproductive organs. Effects of longer exposures are unknown.
Chen, Jianmin, Kaludjerovic, Jovana, Ward, Wendy E.   +2 more
core   +2 more sources

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy

Advanced Science, EarlyView.
Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang, Yedong Tang, Xueling Zhao, Yu Ni, Hualan Zhou, Enhao Zhang, Gaizhen Li, Han Cai, Yinan Wang, James R. Woodgett, Wenbo Deng, Haibin Wang, Zhongxian Lu, Haili Bao, Shuangbo Kong   +14 more
wiley   +1 more source

Condition of the humoral link of immune system at patients with endometrial cancer

Опухоли женской репродуктивной системы, 2014
Examine changes in the parameters reflecting the activation of humoral immune system, the severity of the destructive processesand autoimmune reactions in patients with endometrial cancer .
A. V. Efremov, N. A. Matveevskij, A. N. Trunov, I. D. Safronov   +3 more
doaj   +1 more source

Spectrum of malignancies among the population of adults living with HIV infection in China: A nationwide follow-up study, 2008-2011. [PDF]

, 2019
BackgroundAlthough increasingly studied in high-income countries, there is a paucity of data from the Chinese population on the patterns of cancer among people living with HIV (PLHIV).MethodsWe conducted a nationwide follow-up study using routinely ...
Detels, Roger, He, Na, Mao, Yurong, McGoogan, Jennifer M, Tang, Houlin, Wu, Zunyou, Zhang, Zuo-Feng, Zhu, Weiming   +7 more
core   +2 more sources

Discovery of sexual dimorphism of the laryngeal sac in the common minke whale Balaenoptera acutorostrata

The Anatomical Record, EarlyView.
Abstract Mysticetes, or baleen whales, have an air sac on the ventral surface of the larynx known as the “laryngeal sac.” The primary hypothesis regarding this structure's function is that it is involved in sound production. However, several other functions have been proposed, including air recycling, air storage, and even buoyancy control.
Gen Nakamura, Hiroko Yamada, Ayumi Hirose, Hikari Maeda, Joy S. Reidenberg, Hidehiro Kato, Shinho Park, Yoshihiro Fujise   +7 more
wiley   +1 more source