Results 71 to 80 of about 436,306 (291)

Phosphatidylinositol 3-kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities. [PDF]

, 2019
BackgroundThe phosphatidylinositol 3-kinase (PI3K) pathway is frequently altered in cancer. This report describes the landscape of PI3K alterations in solid tumors as well as co-alterations serving as potential resistance/attenuation mechanisms ...
Albacker, Lee, Ali, Siraj M, Jardim, Denis L, Kurzrock, Razelle, Miller, Vincent A, Millis, Sherri Z, Ross, Jeffrey S   +6 more
core   +1 more source

Neues in der WHO-Klassifikation 2014 der Tumoren des Corpus uteri

Der Pathologe, 2016
ZusammenfassungDie Änderungen in der WHO-Klassifikation 2014 umfassen mehrere Tumorentitäten des Corpus uteri, wobei es einerseits zu einer Vereinfachung der Klassifikation, andererseits zu einer Einführung neuer Entitäten kam.Aus der Fülle der ...
P. U. D. S. F. Lax
semanticscholar   +1 more source

Over one‐third of cancer cases and two‐fifths of cancer deaths in southern China are preventable: Insights from the latest representative population‐based cancer registry data and risk factor survey

International Journal of Cancer, EarlyView.
What's New? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen, Yu Liao, Jiayue Li, Qian Zhu, Xinmei Lin, Bingfeng Han, Li Li, Ru Chen, Ruilin Meng, Ni Xiao, Xueyan Zheng, Xiaojun Xu, Dejian Zhao, Yue Gao, Liming Pu, Ye Wang, Wenqiang Wei, Shaoming Wang   +17 more
wiley   +1 more source

Uterine contractility changes in a perfused swine uterus model induced by local anesthetics procaine, lidocaine, and ropivacaine.

PLoS ONE, 2018
BackgroundLocal anesthetics (LAs) are increasingly used as therapeutics due to their multiple molecular effects. They may be potential agents also in gynecology and reproductive medicine.
Fabian Weinschenk, Ralf Dittrich, Andreas Müller, Laura Lotz, Matthias W Beckmann, Stefan W Weinschenk   +5 more
doaj   +1 more source

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR, Huynh H, Munetoshi Kanayama, Ohtsuki T, Ohtsuki T, Pierro E, Sakae Takeuchi, Shiraga M, Sumio Takahashi, Takaoka M, Tetsuya Maekawa   +10 more
core   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi, Michail Kalinderis, Maria Chatzidimitriou, Liana Fidani   +3 more
wiley   +1 more source

Role of magnetic resonance imaging in the diagnosis of recurrent cancer of the cervix uteri

Опухоли женской репродуктивной системы, 2014
Objective: to define a role of magnetic resonance imaging (MRI) in the follow-up of patients with cancer of the cervix uteri (CCU), who have undergone radiation therapy and chemoradiation therapy and to describe the types of the MRI pattern of recurrent ...
Z. N. Shavladze, T. P. Berezovskaya, A. A. Proshin, L. I. Krikunova, L. S. Mkrtchyan   +4 more
doaj   +1 more source

A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Micro‐and nanoplastics (MNPs) are breakdown products of plastics, and humans are exposed to these particles through air, water, food, and soil. There is a growing concern that human exposure to MNPs negatively impacts health. In this review we will discuss the potential health impact of MNPs on ovarian function and the hypothalamic–pituitary ...
Sanchayana Raghuvir, Shawn Alex, Deborah Clegg   +2 more
wiley   +1 more source

Fibroids and pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The prevalence of uterine fibroids in pregnancy varies between 1.6% and 10.7%. Pregnancies involving uterine fibroids are generally uncomplicated. However, complications can occur, particularly in cases of multiple fibroids, when the fibroids are larger than 5 cm, or when they are located in the lower uterine segment.
Diana Ramasauskaite, Nikhil Purandare, Ivonne Diaz, Greta Kvederaite‐Budre, Titus K. Beyuo, Jolly Beyeza‐Kashesya, Bo Jacobsson   +6 more
wiley   +1 more source

Recurrent vaginal discharge causing by retained foetal bones in a bitch: a case report

Veterinární Medicína, 2009
An 18-month-year old mixed breed bitch was referred to the Animal Hospital of Adnan Menderes University suffering from recurrent serous vaginal discharge for two months.
G. Serin, U. Parin
doaj   +1 more source