Results 111 to 120 of about 1,303,482 (284)

Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski, Rachel Dear, Sanjeev Kumar, Hilary Martin, Dhanusha Sabanathan, Stephen J. Luen, Belinda Yeo   +6 more
wiley   +1 more source

QT dispersion and corrected QT interval in septic patients in correlation with mortality

Egyptian Journal of Critical Care Medicine
Background Sepsis is one of the leading post-surgical or post-traumatic complications in today’s hospitals. This pervasive condition is the major cause of morbidity and mortality in intensive care units worldwide, as well as the leading cause of death in
Ibrahim Mohamed Attia Mahmoud, Hassan Khaled Nagy, Ahmed Mohamed Elsayed Selim, Mohamed Ali Shehata   +3 more
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Differential diagnostic value of P wave dispersion and QT interval dispersion between psychogenic pseudosyncope and vasovagal syncope in children and adolescents

Italian Journal of Pediatrics
Background Both psychogenic pseudosyncope (PPS) and vasovagal syncope (VVS) in children and adolescents are diseases of transient loss of consciousness. It is difficult to distinguish them clinically.
Zifeng Huang, Yi Xu, Shuo Wang, Ping Liu, Xingfang Zen, Yuwen Wang, Fang Li, Runmei Zou, Cheng Wang   +8 more
doaj   +1 more source

Short QT interval syndrome [PDF]

, 1970
Every year, sudden cardiac death (SCD) takes lives of 400 000 American citizens, and in 10-20% ofthe cases, fatal outcome is explained by hereditary pathology.
A. V. Vetluzhsky, I. G. Fomina, A. I. Tarzimanova   +2 more
core  

QT interval abnormalities: Risk factors and perioperative management in long QT syndromes and Torsades de Pointes

, 2013
Electrophysiological abnormalities of the QT interval of the standard electrocardiogram are not uncommon. Congenital long QT syndrome is due to mutations of several possible genes (genotype) that result in prolongation of the corrected QT interval ...
Kaye, Adam M., Volpi-Abadie, Jacqueline, Bensler, J. Michael, Kaye, Alan David, Diaz, James H.   +4 more
core   +1 more source

Treatment sequence with gilteritinib and allogeneic haematopoietic stem cell transplantation in relapsed/refractory FMS‐like tyrosine kinase 3 (FLT3)‐mutated acute myeloid leukaemia patients: A multicentre real‐world study

British Journal of Haematology, EarlyView.
Summary Patients with relapsed or refractory acute myeloid leukaemia (r/r AML) harbouring FMS‐like tyrosine kinase 3 (FLT3) mutations generally have poor prognosis and limited treatment options. The second‐generation FLT3 inhibitor gilteritinib provides better disease control compared to standard relapse therapies and was approved based on two ...
Desiree Kunadt, Sven Zukunft, Christoph Röllig, Stephan Metzelder, Andreas Burchert, Eva Wagner‐Drouet, Oliver Kriege, Christoph Schliemann, Matthias Stelljes, Julian Ronnacker, Wolfgang Bethge, Jan Frederic Weller, Björn Steffen, Gesine Bug, Khouloud Kouidri, Claudia Baldus, Lars Fransecky, Elisa Sala, Uwe Platzbecker, Klaus Metzeler, Sabine Kayser, Inken Hilgendorf, Andreas Hochhaus, Tim H. Brümmendorf, Edgar Jost, Anna Dorottya Doleschall, Thomas Schroeder, Jennifer Kaivers, Lambros Kordelas, Udo Holtick, Julia M. Unglaub, Tim Sauer, Paul Sebastian Jäger, Guido Kobbe, Elena Stauffer, Johanna Tischer, Tobias Herold, Normann Steiner, David Nachbaur, Nicolaus Kröger, Jochen J. Frietsch, Sabrina Kraus, Hermann Einsele, Mathias Hänel, Judith Schaffrath, William Krüger, Anne Brandenburg, Tobias A. W. Holderried, Laura Reinhardt, Markus Maulhardt, Christian Thiede, Martin Bornhäuser, Johannes Schetelig, Jan M. Middeke, Friedrich Stölzel, for the German Cooperative Transplant Study Group and Study Alliance Leukemia (SAL)   +55 more
wiley   +1 more source

Bayesian inference for dynamic Q matrices and attribute trajectories in hidden Markov diagnostic classification models

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Hidden Markov diagnostic classification models capture how students' cognitive attributes evolve over time. This paper introduces a Bayesian Markov chain Monte Carlo algorithm for diagnostic classification models that jointly estimates time‐varying Q matrices, latent attributes, item parameters, attribute class proportions and transition ...
Chen‐Wei Liu
wiley   +1 more source

The risk of treatment-induced QT interval prolongation

, 2022
Objective: QT interval prolongation can increase patients' hospital tay and mortality rate. This study aims to determine the incidence of drug-induced QT interval prolongation and establish which QT Interval measurement method is the most appropriate for
Zavaleta-Monestel,Esteban, Chaverri-Fernández,José Miguel, Fallas-Mora,Abigail, Escalona-Rodríguez,Rocío, Díaz-Madriz,Jose\u301 Pablo, Cordero-García,Eugenia   +5 more
core   +1 more source

The Prolonged Corrected QT-Interval in Children Presented  with Acute Rheumatic Fever

Pakistan Armed Forces Medical Journal
Objective: To determine the frequency of prolonged corrected QT-interval on ECG in children presented with acute rheumatic fever. Study Design: Prospective observational study.
Malik Abid Ali, Ramchand ., Fazal ur Rehman, Abdul Sattar Sheikh, Veena Kumara, Najma Patel   +5 more
doaj   +1 more source