Results 61 to 70 of about 4,575,316 (321)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Thermoelectric Transport Coefficients for Massless Dirac Electrons in Quantum Limit [PDF]

open access: yes, 2013
We perform an analytic calculation of thermoelectric transport coefficients for massless Dirac electrons using the approach based on the Kubo--St\v{r}eda formula and generalized Mott's relation.
Ogata, Masao, Proskurin, Igor
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Assessment of Atmospheric Correction Methods for Sentinel-2 MSI Images Applied to Amazon Floodplain Lakes

open access: yesRemote Sensing, 2017
Satellite data provide the only viable means for extensive monitoring of remote and large freshwater systems, such as the Amazon floodplain lakes. However, an accurate atmospheric correction is required to retrieve water constituents based on surface ...
V. Martins   +5 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Transport Model and Correction of Miniature Measuring Instrument Under Wellbore Temperature and Pressure Fields

open access: yesShiyou jixie, 2023
The miniature measuring instrument records only the physical-field parameters and corresponding time during meansurement while drilling(MWD), but no parameters related to well depth.Based on the relevant study, a wellbore transport model of the miniature
Liao Xingao   +6 more
doaj  

Bayesian Approach for Linear Optics Correction

open access: yes, 2019
With a Bayesian approach, the linear optics correction algorithm for storage rings is revisited. Starting from the Bayes' theorem, a complete linear optics model is simplified as "likelihood functions" and "prior probability distributions".
Cheng, Weixing   +2 more
core   +1 more source

A deep learning approach for 18F-FDG PET attenuation correction

open access: yesEJNMMI Physics, 2018
BackgroundTo develop and evaluate the feasibility of a data-driven deep learning approach (deepAC) for positron-emission tomography (PET) image attenuation correction without anatomical imaging.
Fang Liu   +5 more
semanticscholar   +1 more source

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