Results 41 to 50 of about 7,820,504 (303)

Studying the dynamics of children with autism spectrum disorder and intellectual disability's educational achievement during the junior school

Клиническая и специальная психология
Purpose of the study. Identification and clarification of the dynamics of cognitive and personality educational achievements of primary school students with autistic spectrum disorders and intellectual disorders in the learning process in ...
M.M. Libling, I.D. Antonova, I.A. Kostin, I.N. Nurlygayanov   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

“It’s been like a spiritual awakening for me”: the impacts of traumatic brain injury education with Aboriginal and Torres Strait Islander women in the Australian correctional system

Frontiers in Education
IntroductionA majority of Aboriginal and Torres Strait Islander women in correctional centers report prior experience of traumatic brain injury (TBI) from assault.
Michelle S. Fitts, Michelle S. Fitts, Michelle S. Fitts, Michelle S. Fitts, Jennifer Cullen, Jennifer Cullen, Jennifer Cullen, Rachel Montgomery, Rachel Montgomery, Aunty Glenda Duffy, Aunty Glenda Duffy   +10 more
doaj   +1 more source

Training of Specialists for Working with Special Children at the Kyiv Institute of People's Education

Vìsnik - Kiïvsʹkij nacìonalʹnij unìversitet ìmenì Tarasa Ševčenka: Ìstorìâ, 2020
This paper is devoted to the history of special pedagogy formation at the Kyiv Institute of People's Education. It reconstructs the initial stage of this process, namely the establishment of the medical and pedagogical faculty in 1920, and determines the
O. Liapina
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Booklet-based menstrual hygiene education and its effect on knowledge and attitudes of women

Medisains
Background: Menstrual hygiene is a crucial aspect of reproductive health, particularly for women of reproductive age (WRA) in correctional institutions where access to health education is often limited.
Mustika Hana Harahap, Afrida Sriyani Harahap, Dewi Anggriani Harahap   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Tomorrow Never Comes, But It [Education] Gives You Hope

International Journal of E-learning and Distance Education
Higher education in the correctional environment is endorsed globally as the most effective tool for rehabilitation. Studies from the Global North have researched correctional education and its accessibility, but few of those have focused specifically ...
Bianca Rochelle Parry
doaj   +1 more source