Results 31 to 40 of about 700 (213)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Serious juvenile offenders: classification into subgroups based on static and dynamic charateristics

open access: yesChild and Adolescent Psychiatry and Mental Health, 2017
Background The population in juvenile justice institutions is heterogeneous, as juveniles display a large variety of individual, psychological and social problems.
Sanne L. Hillege   +4 more
doaj   +1 more source

Actualization of the Maqsid Al-Shar'ah in Indonesia: A Case Study of the Spiritual Counting of Prisoners in Judicial Institutions

open access: yesJurnal Fuaduna, 2023
Correctional institutions are undergoing a transformative shift from punitive spaces to acknowledging the humanity of inmates. This study delves into Indonesian correctional facilities' religious-based coaching programs prioritizing inmate protection ...
Aida Humaira   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Fulfillment of The Civil Rights of Prisoners Concerning Legal Cases Relating To Divorce

open access: yesSASI, 2022
Introduction: One type of human rights is civil rights. Correctional institutions are places to build relationships with civil rights concerns. However, in practice, when dealing with divorce cases, they cannot attend the divorce party and are not given ...
Shenti Agustini
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Mental Health of Staff at Correctional Facilities in the United States During the COVID-19 Pandemic

open access: yesFrontiers in Psychiatry, 2022
BackgroundAlthough United States (US) correctional workers (correctional officers and health care workers at correctional institutions) have experienced unprecedented stress during the COVID-19 pandemic, to date, there are no systematic data on the ...
M. Haroon Burhanullah   +5 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Psychodiagnostics of Psychological Readiness of Candidates for Management of Correctional Facilities

open access: yesRUDN Journal of Psychology and Pedagogics, 2019
The article presents the results of an empirical study conducted by the employees of the Research Institute of the Federal Penitentiary Service. The problems of the psychological selection of the employees enrolled in the reserve for the posts of heads ...
Boris G Bovin, Ekaterina M Fedorova
doaj   +1 more source

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