Results 101 to 110 of about 2,002,600 (329)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

EVALUATION OF THE QUALITY OF WHEAT WITH ADDED IMPROVERS

Food and Environment Safety, 2022
One of the main indicators of quality of grain flours is the enzyme content. The most important enzymes on the wheat flour are the a - amylase and the b - amylase.
Amelia BUCULEI, Anca GATLAN, Adriana COJOCARIU   +2 more
doaj  

Electroweak radiative corrections to single Higgs-boson production in e+e- annihilation [PDF]

, 2003
We have calculated the complete electroweak O(alpha) radiative corrections to the single Higgs-boson production processes e+ e- --> nu_l anti-nu_l H (l=e,mu,tau) in the electroweak Standard Model.
't Hooft, A Denner, Altarelli, Bardin, Beenakker, Beenakker, Beenakker, Belanger, Belanger, Bjorken, Boos, Böhm, Böhm, Denner, Denner, Denner, Denner, Denner, Dittmaier, Dittmaier, Dittmaier, Eberl, Eberl, Eberl, Eberl, Eck, Ellis, Fleischer, Hagiwara, Hahn, Hahn, Hahn, Hahn, Hahn, Ioffe, Jegerlehner, Jegerlehner, Jones, Kilian, Kniehl, Kniehl, Küblbeck, Lepage, M Roth, M.M Weber, Mertig, Passarino, S Dittmaier, Sirlin, Stelzer, Wackeroth   +50 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Electronic Monitoring Paradigm: A Proposal for Transforming Criminal Justice in the USA

Laws, 2015
This article proposes a change in public policy that promises to greatly reduce major crime in the United States, protect society, eliminate prison overcrowding, and save taxpayer dollars. This policy would employ electronic monitoring (EM) technology in
Stuart S. Yeh
doaj   +1 more source

Finite-size corrections for logarithmic representations in critical dense polymers

, 2012
We study (analytic) finite-size corrections in the dense polymer model on the strip by perturbing the critical Hamiltonian with irrelevant operators belonging to the tower of the identity. We generalize the perturbation expansion to include Jordan cells,
Affleck, Aharony, Aharony, Blöte, Cardy, Chang, Chin-Kun Hu, Dubail, Ferdinand, Ferdinand, Gaberdiel, Gaberdiel, Henkel, Hu, Hu, Hu, Izmailian, Izmailian, Izmailian, Izmailian, Jensen, Kleban, Kytölä, Lorenz, Morin-Duchesne, Morin-Duchesne, Nickolay Sh. Izmailian, Nigro, Pearce, Philippe Ruelle, Rasmussen, Reinicke, Rohsiepe, Ruelle, Vasseur, Ziff   +35 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Processing Vaccine Misinformation: Recall and Effects of Source Type on Claim Accuracy via Perceived Motivations and Credibility

International Journal of Communication, 2022
This study leverages the persuasion knowledge model (PKM) as a theoretical framework to examine how individuals process attempts at correcting measles, mumps, and rubella vaccine-related misinformation on Facebook. An experiment among U.S.
Michelle A. Amazeen, Arunima Krishna
doaj   +2 more sources

Désistement assisté en contexte formel : une étude de la portée

Criminologie, 2020
Les indicateurs de récidive sont souvent utilisés pour évaluer l’efficacité des interventions réalisées par les acteurs formels du système de justice pénale. Ces études permettent de déterminer « ce qui fonctionne » pour prévenir la récidive. Par contre,
Marie-Pierre Villeneuve, Isabelle F.-Dufour, Stephen Farrall   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source