Results 71 to 80 of about 1,549,917 (266)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The evaluation of the New Zealand's geoid model using the KTH method / Naujosios Zelandijos geoido modelio vertinimas KTH metodu / Оценка модели геоида Новой Зеландии с применением метода КТН

open access: yesGeodesy and Cartography, 2011
We compile a new geoid model at the computation area of New Zealand and its continental shelf using the method developed at the Royal Institute of Technology (KTH) in Stockholm.
Ahmed Abdalla, Robert Tenzer
doaj   +1 more source

Non-oblique Correction in Extenden Technicolor Theory

open access: yes, 1993
We study radiative corrections on $Zb{\bar b}$ vertex generated by the ETC gauge bosons, ``diagonal'' as well as sideways. Although the oblique corrections due to the ETC bosons are small in comparison with the oblique correction due to the technicolor ...
Akiba   +19 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Radiative Corrections to Chargino Production in Electron-Positron Collisions [PDF]

open access: yes, 1997
We discuss the one-loop radiative corrections to the reaction e^+ e^- -> X^+_a X^-_b, for a,b=1,2 where X^+_{1,2} are the charginos of the minimal supersymmetric standard model.
Abreu   +38 more
core   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Supersymmetric Higgs Production in Vector-Boson Fusion

open access: yes, 2009
We present a full calculation of the supersymmetric NLO corrections to Higgs boson production via vector-boson fusion. The supersymmetric QCD corrections turn out to be significantly smaller than the electroweak ones.
Hollik, Wolfgang   +3 more
core   +1 more source

Physics of the Power Corrections in QCD [PDF]

open access: yes, 1999
We review the physics of the power corrections to the parton model. In the first part, we consider the power corrections which characterize the infrared sensitivity of Feynman graphs when the contribution of short distances dominates.
't   +17 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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