Results 71 to 80 of about 418,119 (302)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Kansas Department of Corrections News Release

open access: yes, 2018
The KDOC Will Move Its Salina-Based Office To A New Location On Jan. 12, 2018 An In-Depth Look At Current Trends And Changes Within The Kansas Department Of Corrections (KDOC) is Now Available On The Agency's Website Kansas Prisoner Review Board ...
Kansas. Department of Corrections.
core  

Correction of Accounting Errors through Post Balance Sheet Event Analysis for Romanian Companies

open access: yesEconomies, 2019
The study scope is to present the typology of the events analyzed through our research and their impact on the quality of reported financial data. The objectives of the study are to analyze the vulnerability of enterprises according to methodological ...
Monica Laura Zlati   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Kansas Department of Corrections News Release

open access: yes, 2019
Apprehended: Cal Henry Green III KDOC enacts measures to alleviate staffing shortages at El Dorado Correctional Facility Former KDOC Dental Instructor Faces Criminal Charges Inmate Deaths Under Investigation Visitation Cancelled at Larned Correctional ...
Kansas. Department of Corrections.
core  

Correcting dispersion corrections with density-corrected DFT

open access: yesJournal of Chemical Theory and Computation
Almost all empirical parametrizations of dispersion corrections in DFT use only energy errors, thereby mixing functional and density-driven errors. We introduce density and dispersion-corrected DFT (D2C-DFT), a dual-calibration approach that accounts for density delocalization errors when parametrizing dispersion interactions. We simply exclude density-
Minhyeok Lee   +7 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Kansas Department of Corrections News Release

open access: yes, 2012
Gov. Brownback Signs Bill Establishing Justice Reinvestment Team Working Group to Reduce Corrections Costs, Improve Public Safety -- Hutchinson, Kan., Correctional Facility Honored for Reducing Waste -- Jeremy Barclay Named as Communications Director for
Kansas. Department of Corrections.
core  

Kansas Department of Corrections Annual Report KDOC Annual Report Annual Report Corrections Briefing Report

open access: yes, 2010
"This edition of the Kansas Department of Corrections Annual Report presents the most comprehensive information regarding the Department’s status and operations for Fiscal Year 2010. This edition represents a change in the cycle of distribution which for
Kansas. Department of Corrections
core   +1 more source

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