PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Integrated ERP lean model for quality enhancement and operational excellence in SME based automotive mould manufacturing. [PDF]
Bhaskar A, Devaraju A.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Effects of Bracing Combined With Tele-Rehabilitation-Guided Family Physiotherapeutic Scoliosis-Specific Exercises on Adolescent Idiopathic Scoliosis. [PDF]
Chen T +9 more
europepmc +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Revisiting Key Performance Indicators That Evaluate Food Safety Management Systems: A Short Review. [PDF]
Djekic I, Smigic N.
europepmc +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Manual massage versus foam rolling within the NASM corrective framework: a trial for upper crossed syndrome rehabilitation in university students. [PDF]
Kalantariyan M, Sadeghi M, Samadi H.
europepmc +1 more source
Inventory Management, Spare Parts and Reliability Centred Maintenance for Production Lines [PDF]
Galetto, Fausto
core +2 more sources

