Results 31 to 40 of about 16,736 (244)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
South African Journal of Industrial Engineering, 2019 Response time for repairing rail infrastructure failures remains a challenge in the South African rail industry. The ‘mean time to return’ metric consists of mean time to respond and mean time to repair. This article investigates the mean time to respond
Du Toit, Anerosa +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Journal of Construction Project Management and Innovation, 2011 It is highly desirable but hardly feasible to produce buildings that are maintenance free although much can be done at the design stage to reduce the amount of subsequent maintenance works. The research aim was to examine the various maintenance systems
Zakari Mustapha, Justice Agbevade
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The application of correctness preserving transformations to software maintenance [PDF]
Proceedings International Conference on Software Maintenance ICSM-94, 2000 The size and complexity of hardware and software systems continues to grow, making the introduction of subtle errors a more likely possibility. A major goal of software engineering is to enable developers to construct systems that operate reliably despite increased size and complexity.
J. Paul Gibson +2 more
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Jurnal Teknik Industri, 2005 Mofularity design has been applied in many European countries, especially in industrial assembling and manufacturing. Modularity design cause manufacture process and assembly process easier and cheaper.
Julianingsih Julianingsih +1 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Transient outage model considering corrective and preventive maintenance
Journal of Modern Power Systems and Clean Energy, 2016 Traditional outage model for the power equipment usually focus on the behavior of the equipment under random factors, and the availability of the power equipment in system analysis is usually confined to the steady value.
Guoqiang Ji +3 more
doaj +1 more source