Results 141 to 150 of about 2,493,519 (340)
Two faces of political correctness
, 2022 Ova doktorska disertacija bavi se suvremenim pojmom političke korektnosti i pokazuje njezina dva ‘lica’ – pozitivno i negativno. U radu se prikazuju najznačajniji argumenti zagovornika političke korektnosti (– iz reda feminizma i multikulturalizma) koji ...
Klepač Pogrmilović, Bojana
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Linearizability: a correctness condition for concurrent objects
ACM Transactions on Programming Languages and Systems, 1990 M. Herlihy, Jeannette M. Wing
semanticscholar +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Termination, correctness and relative correctness
, 2016 Over the last decade, research in verification and formal methods has been the subject of increased interest with the need of more secure and dependable software.
Diallo, Nafi
core
Software Evolution by Correctness Enhancement
, 2016 Relative correctness is the property of a program to be more-correct than another with respect to a specification; this property enables us to rank candidate programs in a partial ordering structure whose maximal elements are the correct programs ...
Ghardallou, Wided +5 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Political correctness or contested politics?
, 2017 The aim of this project is to investigate the contested nature of political correctness. As a concept, political correctness appears to mean different things to different people.
Glazier, Sarah E.
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source