Results 181 to 190 of about 2,021,672 (320)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Role of fast-spiking interneurons in modulating across-trial variability and within-trial correlations in the striatum. [PDF]

PLoS Comput Biol
Guo L, Kumar A.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Dissolved organic matter specialization drives temporal dynamics of simplified bacterial communities in a microcosm experiment. [PDF]

ISME Commun
Sandor SR, Scheuerl T, Fonvielle JA, Kemp C, Tanentzap AJ.   +4 more
europepmc   +1 more source

Adaptive rolling runoff forecasting model: Combining multi-source correlated sequences and extreme value encoding

Tao Wang, Jingzhe Liu, Yongming Cheng, Jingjing Duan, Yifei Zhao, Jing Zhao, Peilin Wang, Jiaqi Zhai   +7 more
openalex   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Efficacy of Optically Pumped Magnetometers in Detecting Activity From the Cerebellar Cortex. [PDF]

Hum Brain Mapp
Roos S, Hämäläinen M, Iivanainen J.
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Early Life Protein Intake: Food Sources, Correlates, and Tracking across the First 5 Years of Life

, 2017
Karen Campbell, Gavin Abbott, Miaobing Zheng, Sarah A. McNaughton   +3 more
openalex   +2 more sources

Correlated variability in the W49 water vapour maser source [PDF]

, 1979
G. J. White
openalex   +1 more source