Results 161 to 170 of about 8,113,379 (294)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

CORRELATION BETWEEN SIZE OF THE FRUIT AND THE RESISTANCE OF THE TOMATO SKIN TO PUNCTURE AND ITS RELATION TO INFECTION WITH MACROSPORIUM TOMATO COOKE

, 1920
J. Rosenbaum, Charles E. Sando
openalex   +2 more sources

The Application of Correlation Techniques to Some Acoustic Measurements [PDF]

, 1955
Kenneth Goff
openalex   +1 more source

Abdominal pressure pain thresholds correlate with postoperative pain intensity. [PDF]

Sci Prog
Ghanad E, Weiss C, Taebi N, Klick J, Staff S, Finze A, Dusch M, Reissfelder C, Schmelz M, Yang C.   +9 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Correlation of Serum Potassium Concentrations with the Blood Pressure in Rats Fed a Potassium-Deficient Ration [PDF]

, 1952
SHIRLEY M. ST. GEORGE, Simon Freed, Ray H. Rosenman   +2 more
openalex   +1 more source

Exploring information security compliant behaviors in healthcare Knowledge Process Outsourcing (KPOs). [PDF]

BMC Med Inform Decis Mak
Mahipala C, Perera P.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

CAUSTIC BURNS OF THE ESOPHAGUS AND THEIR SURGICAL MANAGEMENT A CLINICO-EXPERIMENTAL CORRELATION*

, 1953
Thomas H. Burford, Watts R. Webb, Lauren V. Ackerman   +2 more
openalex   +2 more sources

Meta-analysis of surrogate endpoints for overall survival in extensive-stage small-cell lung cancer. [PDF]

ESMO Open
Durer S, Fu P, Chen Z, Dowlati A.
europepmc   +1 more source