Results 31 to 40 of about 3,589,847 (248)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Cluster concepts have been extremely useful in elucidating many problems in physics. Percolation theory provides a generic framework to study the behavior of the cluster distribution. In most cases the theory predicts a geometrical transition at the percolation threshold, characterized in the percolative phase by the presence of a spanning cluster ...
A Coniglio, A Fierro
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BOSE-EINSTEIN CORRELATIONS AS CORRELATIONS OF FLUCTUATIONS [PDF]
Presented at XXXII International Symposium on Multiparticle Dynamics, Alushta, Crimea, Ukraine, September 7-13, 2002. To be published by World Scientific (2003) (style file ws-procs9x6.cls attached)
Zbigniew Wlodarczyk+3 more
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B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
This paper investigates cases in which harms are statistically correlated. When parties are risk averse, correlation plays an important role in the choice between liability rules. Specifically, positively correlated harms favor a liability rule that spreads the risk over a multitude of parties, as in the negligence rule.
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Correlated binomial models and correlation structures [PDF]
12 pages, 7 ...
Shintaro Mori+2 more
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Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Correlation? What Correlation?
In a series of papers [1-5] we have explored the response of a one-electron atom to intense short-pulse laser fields in a reduced-dimension atom model. This 1D "atom" appears to be reasonably realistic, at least in the presence of powerful linearly polarized laser light that induces the single electron to oscillate along the polarization axis.
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