Results 41 to 50 of about 4,205,070 (249)

How far are we? Assessing progress in hepatitis C response towards the WHO 2030 elimination goals by the civil society monitoring in 25 European countries, period 2020 to 2023

Harm Reduction Journal
Background With the advent of direct acting antivirals (DAAs) the World Health Organisation (WHO) adopted global strategy to eliminate hepatitis C virus (HCV) infection by 2030.
Mojca Maticic, J. Cernosa, C. Loboda, J. Tamse, R. Rigoni, E. Duffell, I. Indave, R. Zimmermann, L. Darragh, J. Moura, A. Leicht, T. Windelinckx, M. Jauffret-Roustide, K. Schiffer, T. Tammi   +14 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Exposure to environmental pollutants selects for xenobiotic-degrading functions in the human gut microbiome

Nature Communications
Environmental pollutants from different chemical families may reach the gut microbiome, where they can be metabolized and transformed. However, how our gut symbionts respond to the exposure to environmental pollution is still underexplored.
Francesca De Filippis, Vincenzo Valentino, Giuseppina Sequino, Giorgia Borriello, Marita Georgia Riccardi, Biancamaria Pierri, Pellegrino Cerino, Antonio Pizzolante, Edoardo Pasolli, Mauro Esposito, Antonio Limone, Danilo Ercolini   +11 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A single-center, randomized, open-label, two-period, crossover, fasted bioequivalence study: comparing recombinant human follicle-stimulating hormone for injection (JZB30) with Gonal-f® in healthy Chinese female participants

Frontiers in Pharmacology
ObjectiveThis study aimed to evaluate the pharmacokinetic (PK) bioequivalence, safety, and immunogenicity of recombinant human follicle-stimulating hormone (rhFSH) for injection (code name: JZB30), developed by Chengdu Jingze Biopharmaceutical Co., Ltd.,
Zhuo Chen, Zhuo Chen, Zhuo Chen, Qin Yu, Qin Yu, Qin Yu, Shiyin Feng, Shiyin Feng, Shiyin Feng, Li Mo, Linrui Cai, Linrui Cai, Linrui Cai, Chunfeng Du, Chunfeng Du, Chunfeng Du, Dan Du, Dan Du, Dan Du, Qin Zou, Qin Zou, Qin Zou   +21 more
doaj   +1 more source

INFORMATION APPROACH TO DETERMINING THE TRAFFIC ROUTE BY VEHICLES DRIVERS IN CITIES

Nauka ta progres transportu, 2020
Purpose. Modeling the transport network, streamlining the development and planning of traffic flows, which is possible through the introduction of information technology, leads to better control of the transport system and transport operations. The study
Y. O. Davidich, I. V. Chumachenko, A. S. Galkin, N. V. Davidich, Y. I. Кush   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances

Shiyan dongwu yu bijiao yixue
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang, QUE Changtian, ZHANG Feng, ZHAO Lu, WANG Hongping   +4 more
doaj   +1 more source