Results 81 to 90 of about 6,729,386 (312)

Differentially private correlation clustering [PDF]

, 2021
Correlation clustering is a widely used technique in unsupervised machine learning. Motivated by applications where individual privacy is a concern, we initiate the study of differentially private correlation clustering.
Bun, Mark, Bun, M. (Mark), Kulkarni, Janardhan, Eliáš, M. (Marek), Kulkarni, J. (Janardhan), Bun, Marc, Elias, Marek   +6 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A single-center, randomized, open-label, two-period, crossover, fasted bioequivalence study: comparing recombinant human follicle-stimulating hormone for injection (JZB30) with Gonal-f® in healthy Chinese female participants

Frontiers in Pharmacology
ObjectiveThis study aimed to evaluate the pharmacokinetic (PK) bioequivalence, safety, and immunogenicity of recombinant human follicle-stimulating hormone (rhFSH) for injection (code name: JZB30), developed by Chengdu Jingze Biopharmaceutical Co., Ltd.,
Zhuo Chen, Zhuo Chen, Zhuo Chen, Qin Yu, Qin Yu, Qin Yu, Shiyin Feng, Shiyin Feng, Shiyin Feng, Li Mo, Linrui Cai, Linrui Cai, Linrui Cai, Chunfeng Du, Chunfeng Du, Chunfeng Du, Dan Du, Dan Du, Dan Du, Qin Zou, Qin Zou, Qin Zou   +21 more
doaj   +1 more source

Robustness versus efficiency for nonparametric correlation measures. [PDF]

Nonparametric correlation measures at the Kendall and Spearman correlation are widely used in the behavioral sciences. These measures are often said to be robust, in the sense of being resistant to outlying observations.
Croux, Christophe, Dehon, Catherine
core  

VaR-implied tail-correlation matrices : [Version October 2013] [PDF]

, 2013
Empirical evidence suggests that asset returns correlate more strongly in bear markets than conventional correlation estimates imply. We propose a method for determining complete tail correlation matrices based on Value-at-Risk (VaR) estimates.
Mittnik, Stefan
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Analysis of Common Causes of Out-of-Specification Results in the Test for Depressor Substances

Shiyan dongwu yu bijiao yixue
According to General Chapter 1145 of Division IV in the Chinese Pharmacopoeia (2020 Edition), the test for depressor substances is a common method for drug testing.
TONG Xiyang, QUE Changtian, ZHANG Feng, ZHAO Lu, WANG Hongping   +4 more
doaj   +1 more source

Novel health systems service design checklist to improve healthcare access for marginalised, underserved communities in Europe

BMJ Open, 2020
Background Marginalised communities such as homeless people, people who use drugs (PWUD), lesbian, gay, bisexual, transgender and intersex people (LGBTI), prisoners, sex workers and undocumented migrants are at high risk of poor health and yet face ...
Jeffrey V Lazarus, Freek Spinnewijn, Lee Baker, Mario Cascio, Denis Onyango, Eberhard Schatz, Alyna C Smith   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

No dose adjustment required for warfarin or metformin when coadministered with the novel GLP-1 receptor agonist ecnoglutide: an open-label, fixed-sequence, crossover study

Frontiers in Pharmacology
ObjectiveTo characterize the drug-drug interaction (DDI) profile of the novel, long-acting GLP-1 receptor agonist ecnoglutide (XW003) with two widely co-prescribed drugs: metformin and narrow therapeutic index agent, warfarin.MethodsIn this open-label ...
Zhuo Chen, Zhuo Chen, Zhuo Chen, Zhuo Chen, Chunfeng Du, Chunfeng Du, Chunfeng Du, Chunfeng Du, Linrui Cai, Linrui Cai, Linrui Cai, Linrui Cai, Shiyin Feng, Shiyin Feng, Shiyin Feng, Shiyin Feng, Qin Zou, Qin Zou, Qin Zou, Qin Zou, Weiyi Guo, Weiyi Guo, Weiyi Guo, Weiyi Guo, Fengshan Li, Fengshan Li, Fengshan Li, Fengshan Li, Dan Du, Dan Du, Dan Du, Dan Du, Feng Hu, Feng Hu, Feng Hu, Feng Hu, Xiaohong Liu, Xiaohong Liu, Xiaohong Liu, Xiaohong Liu, Yalin Huang, Yalin Huang, Yalin Huang, Yalin Huang, Shuxia Shi, Shuxia Shi, Shuxia Shi, Shuxia Shi, Wei Shi, Wei Shi, Wei Shi, Wei Shi, Qin Yu, Qin Yu, Qin Yu, Qin Yu, Lingli Zhang, Lingli Zhang, Lingli Zhang, Lingli Zhang, Lingli Zhang, Lei Guan, Liu Yang, Yao Li, Rui Liu, Jing Ning, Ming Yang, Qing Zheng   +67 more
doaj   +1 more source