Results 71 to 80 of about 8,186,859 (287)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Eco-physiological mechanisms age womans obesity: multiple correlation physiological parameter

open access: yesRUDN Journal of Ecology and Life Safety, 2011
In addressing global environmental issues relevant is the multidimensional evaluation system: biomedical, social, economic, moral. Singularity of environmental diseases is that they affect every individual, but only certain part of the population.
M A Gavrilov   +5 more
doaj  

Simultaneous Determination of Ten Nucleosides in New Selenium-enriched Bamboo Shoots by HPLC-FP

open access: yesShipin gongye ke-ji
Objective: To establish a method for simultaneous determination of cytosine, uracil, cytidine, hypoxanthine, uridine, thymidine, adenine, guanosine, thymidine and adenosine in different selenium-rich bamboo shoots.
Xinrui QIN   +9 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Changes in Surface Runoff and Temporal Dispersion in a Restored Montane Watershed on the Qinghai–Tibetan Plateau

open access: yesLand
Surface runoff is a major component of the hydrological cycle, and it is essential for supporting the ecosystem services provided by grassland and forest ecosystems.
Xiaofeng Ren   +9 more
doaj   +1 more source

Phase and vortex correlations in Josephson-junction arrays at irrational frustration

open access: yes, 2008
Phase coherence and vortex order in a Josephson-junction array at irrational frustration are studied by extensive Monte Carlo simulations using the parallel tempering method.
Granato, Enzo
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Appropriate Application of Organic Fertilizer Can Effectively Improve Soil Environment and Increase Maize Yield in Loess Plateau

open access: yesAgronomy
Fertilization has a significant impact on soil nutrients and microbiological properties, which, in turn, affect crop yield. However, the specific effects of organic and inorganic fertilizers on soil fertility and microbial characteristics in maize fields,
Yingying Xing   +3 more
doaj   +1 more source

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