Results 111 to 120 of about 699,825 (321)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Financialization, crisis and commodity correlation dynamics [PDF]

open access: yes, 2010
We study conditional volatility and correlation dynamics for returns to commodity fu- tures, stocks and bonds, from May 1990-July 2009 using DSTCC- GARCH.
Silvennoinen, A, Thorp, SJ
core  

Financialization, Crisis and Commodity Correlation Dynamics [PDF]

open access: yes
We study bi-variate conditional volatility and correlation dynamics for individual commodity futures and financial assets from May 1990-July 2009 using DSTCC-GARCH (Silvennoinen and Terasvirta 2009).
Annastiina Silvennoinen, Susan Thorp
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Determinants of sovereign risk premia for European emerging markets [PDF]

open access: yes
This paper analyses the determinants of the changes in sovereign bond spreads in emerging European markets before and during the recent global financial crisis.
Marko Primorac, Mirna Dumicic
core  

CAPITAL MARKET CORRELATIONS STRUCTURE DURING THE COVID-19 CRISIS

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2020
The current Covid-19 crisis had a negative impact on the society and economy in general and on the capital markets in particular. Even if, at least in the first few months, the pandemics acted only as an exogenous shock upon the capital markets, its influence was clearly reflected in negative market returns, even if the economic activity hadn’t yet ...
openaire   +1 more source

[Correlations between asthmatic crisis and meteorological conditions in Rosario, Argentina].

open access: yesAllergologia et immunopathologia, 1985
The aim of this work was to find out whether there is any relationship between the climate in Rosario City, Argentina, and the frequency of asthmatic crises, and whether it would be possible to use weather forecasts to support therapeutic measures. Synoptic and statistical metereological analyses, were used, and the following results achieved: The 721 ...
R G, Arnolt   +3 more
openaire   +1 more source

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