We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Dynamic linkages of stock prices among G7 countries: effects of the American financial crisis [PDF]
In this paper, we use the cross-correlation function developed by Cheung and Ng (1996) to investigate the dynamic linkages among G7 countries in the mean and volatility of stock prices from June 2, 2003, through July 31, 2010.
Haifeng Xu, Shigeyuki Hamori
core
The Dynamics of Volatility and Correlation During Periods of Crisis: Implications for Active Asset Management [PDF]
Marcello Esposito
openalex
Sickle Cell Crisis and Emergency Department Visits: Is There a Correlation with the Weather and Seasons? [PDF]
Mehvish Ahmed +4 more
openalex +1 more source
CORRELATION BETWEEN COPING STRATEGIES AND ROLE CRISIS [PDF]
openaire +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Correlation of demographic-economic evolutions in Romania after the 2008 economic crisis [PDF]
Adriana Veronica Litră
openalex
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
THE EU POSITION IN THE WORLD ECONOMY IN THE CONTEXT OF CURRENT ECONOMIC CRISIS: REFLECTIONS ON THE G20 MEETING OF APRIL 2009 [PDF]
The article focuses on the changes in the economic balance of power in the world economy, particularly as result of long term trends related to globalization and in correlation with the implications of the current economic crisis. The analysis is done in
Florin Bonciu
core

