Results 161 to 170 of about 17,197 (218)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

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Correlation functions and factorial correlator data

Physical Review D, 1991
The close connection between factorial moments and factorial correlators as integrals of the same underlying correlation function is explored, leading to extensions of sum rules previously suggested. Cumulants, which were previously found to be the fundamental building blocks for moments, have been analogously defined for the correlators also ...
, Eggers, , Carruthers, , Lipa, , Sarcevic   +3 more
openaire   +2 more sources

Correlation Functionals

Journal of Mathematical Physics, 1965
The correlations between positions of particles in classical equilibrium statistical mechanics are usually expressed by correlation functions. It can be seen that if the correlation functions of a system are known, its configurational entropy per unit volume is already determined (independently of the interaction potential or other thermodynamical ...
openaire   +2 more sources

Correlation Functions as Hydrodynamic Green's Functions

Physical Review, 1968
A formal solution for the thermodynamic variables describing a system in a nonequilibrium state is given in terms of space- and time-dependent correlation functions. The solution during the hydrodynamic stage is also given by the Green's function solution to the hydrodynamic equations. The correlation functions contain information, not contained in the
Dufty, J. W., McLennan, J. A.
openaire   +1 more source

Functional Neuroimaging Correlates of Functional Amnesia

Memory, 1999
Especially in the field of memory encoding and retrieval, the results of functional neuroimaging have provided new insights in anatomico-functional interactions. In particular this holds true for the role of the prefrontal cortex in mnestic information processing, for the contribution and participation of the two hemispheres in various processes of ...
openaire   +2 more sources

Thermodynamic functions as correlation-function integrals

The Journal of Chemical Physics, 2013
Expressions of some thermodynamic functions as correlation-function integrals, such as the Ornstein-Zernike integral, the Kirkwood-Buff integrals, and the integral formulas for virial coefficients, are recalled. It is noted, as has been remarked before, that the choice of molecular centers from which intermolecular distances are measured is arbitrary ...
K, Koga, B, Widom
openaire   +2 more sources

Fitting the correlation function

Applied Optics, 2000
The whole correlation function of the intensity of scattered light is usually determined from a single realization of the photocurrent. As a result, the values of the correlation function at different delay times are not statistically independent. A standard least-squares fitting procedure is not optimal for an analysis of such data.
openaire   +2 more sources