Results 201 to 210 of about 6,674,387 (259)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Identifying the necrotic zone boundary in tumour spheroids with pair-correlation functions. [PDF]

J R Soc Interface, 2016
Dini S, Binder BJ, Fischer SC, Mattheyer C, Schmitz A, Stelzer EH, Bean NG, Green JE.   +7 more
europepmc   +1 more source

DQC1-hardness of estimating correlation functions

Out-of-Time-Order Correlation function measures transport properties of dynamical systems. They are ubiquitously used to measure quantum mechanical quantities, such as scrambling times, criticality in phase transitions, and detect onset of thermalisation.
Moulik, Subhayan Roy, Strelchuk, Sergii
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

On the use of two-time correlation functions for X-ray photon correlation spectroscopy data analysis. [PDF]

J Appl Crystallogr, 2017
Bikondoa O.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Small-angle neutron scattering correlation functions of bulk magnetic materials. [PDF]

J Appl Crystallogr, 2015
Mettus D, Michels A.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Advances in milestoning. II. Calculating time-correlation functions from milestoning using stochastic path integrals. [PDF]

J Chem Phys, 2018
Grazioli G, Andricioaei I.
europepmc   +1 more source

Using coherent X-rays to follow dynamics in amorphous ices.

Environ Sci Atmos, 2022
Ladd-Parada M, Li H, Karina A, Kim KH, Perakis F, Reiser M, Dallari F, Striker N, Sprung M, Westermeier F, Grübel G, Nilsson A, Lehmkühler F, Amann-Winkel K.   +13 more
europepmc   +1 more source