Results 41 to 50 of about 71,791 (282)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

L’anarchiste et la philosophe : Antonio Atarés et Simone Weil (1941-1951)

open access: yesCahiers de Civilisation Espagnole Contemporaine, 2012
The correspondence between Simone Weil and Antonio Atarés in 1941 and 1942 has resulted in a striking imbalance. Whereas we are amply informed about the spiritual and philosophical preoccupations of the French philosopher during the period and have ...
Bernard Sicot
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Correspondance

open access: yes, 1989
Correspondance. In: L'Homme, 1989, tome 29 n°109.

core   +4 more sources

Le déjà-plus et l’à-jamais : la lettre tabucchienne

open access: yesItalies, 2007
L’axe du temps et celui de l’espace se croisent chez Tabucchi au point zéro de l’absence. L’histoire des liens est celle de liens défunts, et l’écriture l’éternel constat que ce qui était n’est plus. Être là, alors que l’autre n’y est plus ; penser hier,
Perle Abbrugiati
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

La correspondance Mcmahon-Hussein première phase du plan de partition du proche-orien [PDF]

open access: yes, 2017
Entre 1915 et 1916, la correspondance entre le haut commissaire en Égypte Henry McMahon et Sayyed Hussein Ben Ali, le chérif de la Mecque préfigure, avant les accords Sykes-Picot et la Déclaration Balfour, la partition coloniale du Proche-Orient.
Guediri, Kaoutar
core  

Rilievi sulla scrittura satirica di Carlantonio Pilati

open access: yesItalies, 2000
Marco Cerruti met en relief l’intérêt des Lettere di un viaggiatore filosofo de Carlantonio Pilati, notamment celui des passages relatifs au Royaume de Naples et à la Calabre que l’Illuministe parcourt animé d’une vis polémique sympathique car atténuée ...
Marco Cerruti
doaj   +1 more source

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