Results 81 to 90 of about 193,860 (248)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Mawasiliano (Correspondence/Correspondance)
T.B. Kortz +3 more
openaire +6 more sources
Eduarda Mansilla y Victor Hugo: un breve intercambio epistolar marcando los inicios de la literatura francófona de Argentina [PDF]
Argentine francophone literature originates with Eduarda Mansilla’s novel Pablo ou la vie dans les Pampas, published in 1869; the author forwards a copy to Victor Hugo, generating a brief correspondence.
Carlos Alvarado-Larroucau
doaj
« Comme si c’était chez moi » : Joseph Zobel à Paris à travers ses lettres (1946-1947)
Jenny Zobel, fille de l’écrivain martiniquais Joseph Zobel, et Emily Zobel Marshall, petite-fille de Joseph Zobel, ont découvert récemment des manuscrits inédits de leur père et grand-père.
Emily Zobel Marshall, Jenny Zobel
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
En passant par la Crimée (été 1855)
Sont présentées deux lettres inédites de Vincenzo Ricasoli rédigées en pleine guerre de Crimée, en 1855. Frère du « baron de fer » Bettino Ricasoli, il devait plus tard devenir général puis sénateur.
Georges Virlogeux
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Peculiar Velocities of Galaxy Clusters
We investigate the peculiar velocities predicted for galaxy clusters by theories in the cold dark matter family. A widely used hypothesis identifies rich clusters with high peaks of a suitably smoothed version of the linear density fluctuation field ...
Colberg, J. M. +7 more
core +1 more source

