Results 111 to 120 of about 1,125,708 (292)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Le lettere di d’Annunzio a Re Riccardi
Archivio d’Annunzio, 2014 Adolfo Re Riccardi was a theatrical producer who was active in the first two decades of the 20th century and staged some of Gabriele d’Annunzio’s dramas.
Salvatore, Eugenio
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Altre Modernità, 2020 Between 1941 and 1942 Curzio Malaparte, one of the most troubled writers in Fascist Italy, was sent by Il Corriere della Sera on the Russian Front as a war correspondent, to write under the supervision of redactor Aldo Borelli and the harsh control of ...
Carla Giacobbe
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Enseñanza de las Ciencias, 2017 Pollination by animals is a key process involved in flowering plants reproduction. In the educational context, this topic is rarely addressed from the plant-pollinator interaction point of view, and its importance is poorly recognized by the students ...
Matias Cristian Baranzelli +10 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Topical Issues in Publishing the Letters of F. M. Dostoevsky and His Correspondents
Неизвестный Достоевский, 2020 The article provides an overview of the editorial principles in publishing F.M. Dostoevsky’s epistolary heritage. An analysis of these principles allows to discuss the evolution of goals and objectives of the researchers involved in the preparation of Dostoevsky’s and his correspondents’ letters for publication.
openaire +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source