Results 161 to 170 of about 3,829 (260)

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang, Xin‐Qi Pei, Ji‐Ping Sun, Chen‐Hui Ma, Xin‐Yang Wang, Xu‐Dong Li   +5 more
wiley   +1 more source

Implementing a Digital Mental Health Intervention-the Lumi Nova App-to Support Children With Anxiety in Economically Disadvantaged Areas: Mixed Methods Study.

J Med Internet Res
Whelan P, Tranter H, Carter LA, Sainsbury J, Rathee M, Stockton-Powdrell C, Bolton N, Abel KM.   +7 more
europepmc   +1 more source

Interventional strategies for the management of the disruptive physician: A systematic review. [PDF]

Future Healthc J
Chen AM.
europepmc   +1 more source

CO2 Fluxes and Soil Responses to Straw and Herbicide in Peanut

Land Degradation &Development, EarlyView.
ABSTRACT Peanut cultivation plays an important agronomic role in Brazil, especially in rotation with sugarcane, promoting biological nitrogen fixation and improving soil quality. This study aimed to test the hypothesis that the combined use of sugarcane mulch, peanut cultivation, and herbicide application would affect soil CO₂ fluxes, soil chemical ...
Heytor Lemos Martins, Vitor Adriano Benedito, Arianis Ibeth Santos‐Nicolella, Treyce Stephane Cristo Tavares, Rodrigo Baratiere Perim, Vanesca Korasaki, Newton La Scala Jr., Pedro Luís da Costa Aguiar Alves   +7 more
wiley   +1 more source

Terrestrial and Airborne Laser Scanning Dataset of Trees in the Shivalik Range, India with Field Measurements and Leaf-Wood Classifications. [PDF]

Sci Data
Ali M, Biswas A, Iglseder A, Kumar V, Kumar S, Gupta S, Hollaus M, Pfeifer N, Lohani B.   +8 more
europepmc   +1 more source

Whole‐Genome Bisulfite Sequencing Identifies Blood‐Based DNA Methylation Biomarker for Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao, Sijia Shen, Junjie Zhang, Ying Xu, Jing Peng, Hainv Gao, Lanjuan Li   +6 more
wiley   +1 more source

Projected extreme temperature event-attributable dementia deaths in China: a climate-ageing-adaptation framework. [PDF]

EBioMedicine
Zhang R, Li Y, Zheng H, Chen M, Zhao J, Hu Y, Jia A, Guo Q, Wang S, Wang L, Niu R, Wang C, Han Q, Du X, Jin L, Li S, Chen Q, Meng Y, Wu S, Lu B, Zhao R, Bi P, Wu J.   +22 more
europepmc   +1 more source

VPS13A Deficiency Leads to Impaired Lipid Distribution and Alteration of Mitochondrial Calcium Homeostasis in Fibroblasts of VPS13A Disease Patients

Movement Disorders, EarlyView.
Abstract Background Membrane contact sites are crucial for the exchange of ions or lipids and thus are critical for the function and maintenance of organelles. VPS13A is a membrane‐residing, bridge‐like protein connecting two membranes to enable bulk lipid transfer. Loss‐of‐function mutations in the VPS13A gene cause VPS13A disease.
Dajana Grossmann, Adrian Spranger, Emily Fischer, Johanna W. Schubarth, Jenny Leopold, Hannes Glaß, Sebastian Klicker, My Uyen Dang Thi, Anna Elisabeth Bartalis, Andreas Hermann, Kevin Peikert   +10 more
wiley   +1 more source

A systematic meta-review of interventions to prevent and manage delirium in the Intensive Care Unit: Part 1 - Pharmacological interventions. [PDF]

Crit Care
L Jones K, Kundakci B, Booth A, Falzon L, Gibbison B, Pufulete M, OPTIC consortium.   +6 more
europepmc   +1 more source