Results 31 to 40 of about 3,829 (260)

Research of selection of reference stations in mine area deformation monitoring based on JSCORS

open access: yesGong-kuang zidonghua, 2015
Based on data information of Jiangsu Province continuously operating reference stations, the influence of the number and distribution of CORS reference stations to the solution accuracy of GPS network data were discussed combining with 6 stations ...
CHEN Zhongwei   +3 more
doaj   +1 more source

Future of National Reference Frames – from static to kinematic? [PDF]

open access: yesGeodesy and Cartography, 2018
Technical development, new applications and requests for increased accuracy in georeferencing are setting new demands for accuracy and reliability of reference frames.
Markku Poutanen, Pasi Häkli
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Geodetic advances in Estonia 2018–2022

open access: yesJournal of Geodetic Science, 2023
Geodetic advances in Estonia within the Nordic Geodetic Commission activity term 2018–2022 are reviewed. The new Estonian height and gravity systems and a new geoid model, EST-GEOID207, have been implemented. A national global navigation satellite system
Kollo Karin, Ellmann Artu
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Cor pulmonale

open access: yesChronic Respiratory Disease, 2009
The term “cor pulmonale” is still popular but there is presently no consensual definition and it seems more appropriate to define the condition by the presence of pulmonary hypertension (PH) resulting from diseases affecting the structure and/or the function of the lungs: PH results in right ventricular enlargement and may lead with time to right ...
E, Weitzenblum, A, Chaouat
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Assessing People’s Willingness to Participate in Counter Violent Extremism Programmes: The development of Counterradicalism Readiness Scale (CoRS)

open access: yesBulletin of Counseling and Psychotherapy, 2022
Counterterrorism approach in Indonesia emphasizes on prevention rather than prosecution. Radicalism could lead to the acts of terrorism; hence, in terms of terrorism prevention, the role of civil society is significant in avoiding radicalization of ...
Zora A. Sukabdi
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Jeddah CORS/ VRS: Design, Establishment, and Testing [PDF]

open access: yesPort Said Engineering Research Journal, 2013
Geodetic infrastructure traditionally consisted of physical (passive) geodetic marks in the ground and the associateddata, including coordinates and datum.
doaj   +1 more source

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