Results 41 to 50 of about 3,829 (260)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Effect of using different satellite ephemerides on GPS PPP and post processing techniques

open access: yesGeodesy and Cartography, 2021
The orbital error is one of the errors in GPS which affect the accuracy of GPS positioning. In this research GPS broadcast, ultra-rapid, rapid and precise satellite ephemerides are used for processing different baseline lengths among some CORS stations ...
Khaled Mahmoud Abdel Aziz   +1 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Assessing Wave Attenuation With Rising Sea Levels for Sustainable Oyster Reef-Based Living Shorelines

open access: yesFrontiers in Built Environment, 2022
In densely populated coastal areas with sea-level rise (SLR), protecting the shorelines against erosion due to the wave impact is crucial. Along with many engineered structures like seawalls and breakwaters, there are also green structures like ...
Reza Salatin   +4 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Linear and Nonlinear Deformation Effects in the Permanent GNSS Network of Cyprus

open access: yesSensors, 2020
Permanent Global Navigation Satellite Systems (GNSS) reference stations are well established as a powerful tool for the estimation of deformation induced by man-made or physical processes.
Chris Danezis   +2 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Cor triatrium dexter [PDF]

open access: yesHeart, 1970
A case of cor triatrium dexter is described in which the patient had been independently assessed in two cardiological centres as having a form of Ebstein's anomaly. The differential diognosis is discussed.
D, Verel, J, Pilcher, D M, Hynes
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Povečanje zanesljivosti GNSS-omrežij SIGNAL in 0. red (= Increase of reliability of the SIGNAL and Zero-Order GNSS networks) [PDF]

open access: yesGeodetski Vestnik, 2019
For more than a decade, the GNSS Service at the Geodetic Institute of Slovenia has been managing the national GNSS CORS network SIGNAL, and since 2016 also the GNSS part of the national Zero-Order Geodetic Network.
Klemen Ritlop   +6 more
doaj   +1 more source

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