Results 71 to 80 of about 34,751 (324)
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Advanced Science, EarlyView.Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu +13 more
wiley +1 more source
Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Advanced Science, EarlyView.eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin +3 more
wiley +1 more source
Array-aided CORS network ambiguity resolution
, 2014 Array-aided precise point positioning (A-PPP) is a measurement concept that uses Global Navigation Satellite System (GNSS) data, from multiple antennas in an array of known geometry, to realize the improved GNSS parameter estimation. In this contribution
Li, Bofeng, Teunissen, Peter
core +2 more sources
Tongxin xuebao, 2006 The positioning Precision testing methods of CORS were introduced in detail.Based on the testing method of static fixed point and the method of comparing with the post-processing positioning result,the paper put forward land regular geometrical track ...
TANG Wei-ming1 +4 more
doaj +2 more sources
CARR - CORS Dictionnaire historique et biographique des Généraux Français (-) Carr - Cors (Tome Quatrième) ([2]r) Cover ( - ) Titelseite ([1]r) Titelseite ([2]r) Text ([1]) Additions, Renvois ...
Courcelles, Jean Baptiste Pierre Jullien +2 more
core
Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding
Advanced Science, EarlyView.Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun +6 more
wiley +1 more source
Journal of the American College of Cardiology, 2013 I remember first being introduced to the term cor pulmonale in medical school, which was used to describe right heart failure due to chronic lung disease, and I still have a mental picture of the typical patient as a former heavy smoker, dyspneic at rest, and cyanotic with neck vein distention ...
openaire +2 more sources
Structure property correlations of microgels with complex architectures
, 2019 Cors M. Structure property correlations of microgels with complex architectures.
Cors, Marian
core