Results 51 to 60 of about 8,076 (300)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Large subcapsular hematoma of the liver due to faja corset: a rare case report

open access: yesEgyptian Liver Journal, 2020
Background Subcapsular hematoma of the liver is a potentially life-threatening but extremely rare condition. It is often caused by a blunt trauma or other predisposing conditions such as a liver tumor, intra-tumor hemorrhage, surgery, preeclampsia, liver
Sheharyar Minhas   +3 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Predicting Intra-Abdominal Adhesions in Repeat Cesarean Sections: Scar Tissue Characteristics, Striae Gravidarum, and Corset Use

open access: yesClinical and Experimental Obstetrics & Gynecology
Background: This study evaluated whether abdominal scar tissue characteristics, duration of corset use, and striae gravidarum (SG) density are associated with the severity of intra-abdominal adhesions (IAA) in repeat cesarean sections (
Yusuf Ziya Kizildemir   +4 more
doaj   +1 more source

Syncytial germline architecture is actively maintained by contraction of an internal actomyosin corset

open access: yesNature Communications, 2018
Germline cells in many species are fused to form a syncytium but the mechanics behind the maintenance of these structures are poorly defined. Here, the authors propose an inner contractile actomyosin corset provides a supportive framework to maintain ...
Agarwal Priti   +6 more
doaj   +1 more source

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro   +6 more
wiley   +1 more source

Yatisi Corset trade card

open access: yes, 1886
This is a trade card advertising Yatisi 'Fits Easy' Corset, featuring a portrait of First Lady Frances Clara Folsom Cleveland, labeled here as "The Lady of the White House," wife of President Grover Cleveland, who held office from 1886-1889 and again ...
Yatisi Corset
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‘The men who wear corsets are just ordinary people, Officers, aye and Privates too’: Fragments of biography of a gentleman’s corset in mid-twentieth century Britain

open access: yes, 2021
The corset is a concealed garment that is closely associated with femininity due to its significant place in women’s underwear and fashions for hundreds of years.
Sprecher, Danielle
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Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

Surgical Corset

open access: yes, 2010
Surgical corset with two metal back supports (non-flexible) eight further supports (four with flexible plastic). Blanket pad to centre back, two elstic panels to sides. Eleven steel hooks and three rows of eleven loops.
The Betty Smithers Design Collection at Staffordshire University   +1 more
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