Results 231 to 240 of about 220,716 (304)

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

Modeling and simulation of neocortical micro- and mesocircuitry (Part I, anatomy). [PDF]

Elife
Reimann MW, Bolaños-Puchet S, Courcol JD, Egas Santander D, Arnaudon A, Coste B, Delalondre F, Delemontex T, Devresse A, Dictus H, Dietz A, Ecker A, Favreau C, Ficarelli G, Gevaert M, Herttuainen J, Isbister JB, Kanari L, Keller D, King J, Kumbhar P, Lapere S, Lazovskis J, Lu H, Ninin N, Pereira F, Planas J, Pokorny C, Riquelme JL, Romani A, Shi Y, Smith JP, Sood V, Srivastava M, Van Geit W, Vanherpe L, Wolf M, Levi R, Hess K, Schürmann F, Muller EB, Markram H, Ramaswamy S.   +42 more
europepmc   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Feeding, Emotion, and the Brain Stem: The Interesting Case of the Mesencephalic Trigeminal Nucleus. [PDF]

Brain Sci
Turnbull OH.
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Recurrent femoral stem fractures in Dorr A femurs: Lessons learned and a call for alternative strategies. [PDF]

World J Methodol
Lucero CM, Luco JB, Albani Forneris A, Buttaro MA.   +3 more
europepmc   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

White matter microdissection of the medial aspect of the brain: 2-dimensional video demonstration. [PDF]

Acta Neurochir (Wien)
Zanuttini L, Staartjes VE, Menna G, Chen SC, Lin CF, Hsu SPC, Martins C, Wen HT, Colacicco G, Kadri PAS, Krayenbühl N, Serra C, Türe U.   +12 more
europepmc   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Gut microbiota shape diurnal rhythms of amino acid metabolism in the mouse prefrontal cortex. [PDF]

Mol Metab
Tofani GSS, Cryan JF.
europepmc   +1 more source