Results 51 to 60 of about 97,470 (305)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Abnormal Changes of Brain Cortical Anatomy and the Association with Plasma MicroRNA107 Level in Amnestic Mild Cognitive Impairment

open access: yesFrontiers in Aging Neuroscience, 2016
MicroRNA107 (Mir107) has been thought to relate to the brain structure phenotype of Alzheimer’s disease. In this study, we evaluated the cortical anatomy in amnestic mild cognitive impairment (aMCI) and the relation between cortical anatomy and plasma ...
Tao eWang   +9 more
doaj   +1 more source

Patterns of Individual Variation in Visual Pathway Structure and Function in the Sighted and Blind. [PDF]

open access: yesPLoS ONE, 2016
Many structural and functional brain alterations accompany blindness, with substantial individual variation in these effects. In normally sighted people, there is correlated individual variation in some visual pathway structures.
Geoffrey K Aguirre   +11 more
doaj   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger   +16 more
wiley   +1 more source

Rhizome and root anatomy of 14 species of Bromeliaceae

open access: yesRodriguésia
The anatomy of rhizomes and roots of 14 species of Bromeliaceae that occur in the cerrado biome were studied with the aim of pointing out particular anatomical features of the family and possible adaptations related to the environment.
Suzana Lúcia Proença   +1 more
doaj   +1 more source

Is There a Canonical Cortical Circuit for the Cholinergic System? Anatomical Differences Across Common Model Systems

open access: yesFrontiers in Neural Circuits, 2018
Acetylcholine (ACh) is believed to act as a neuromodulator in cortical circuits that support cognition, specifically in processes including learning, memory consolidation, vigilance, arousal and attention. The cholinergic modulation of cortical processes
Jennifer J. Coppola, Anita A. Disney
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

Category-Selectivity in Human Visual Cortex Follows Cortical Topology: A Grouped icEEG Study. [PDF]

open access: yesPLoS ONE, 2016
Neuroimaging studies suggest that category-selective regions in higher-order visual cortex are topologically organized around specific anatomical landmarks: the mid-fusiform sulcus (MFS) in the ventral temporal cortex (VTC) and lateral occipital sulcus ...
Cihan Mehmet Kadipasaoglu   +4 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

CROSSTALK BETWEEN PROTOCADHERIN 8 AND TRANSCRIPTION FACTOR DBX1 REGULATE CELL FATE IN THE DEVELOPING CEREBRAL CORTEX

open access: yesIBRO Neuroscience Reports, 2023
Andrzej W Cwetsch   +11 more
doaj   +1 more source

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