Results 81 to 90 of about 222,541 (260)

Resting state functional connectivity in the default mode network and aerobic exercise in young adults [PDF]

open access: yes, 2017
Around the world Alzheimer’s Disease (AD) is on the rise. Previous studies have shown the default mode network (DMN) sees changes with AD progression as the disease erodes away cortical areas.
Goss, Andrew
core  

Developmental Lead and/or Prenatal Stress Exposures Followed by Different Types of Behavioral Experience Result in the Divergence of Brain Epigenetic Profiles in a Sex, Brain Region, and Time-Dependent Manner: Implications for Neurotoxicology. [PDF]

open access: yes, 2017
Over a lifetime, early developmental exposures to neurocognitive risk factors, such as lead (Pb) exposures and prenatal stress (PS), will be followed by multiple varied behavioral experiences.
Cory-Slechta, Deborah A.   +3 more
core   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Censoring Distances Based on Labeled Cortical Distance Maps in Cortical Morphometry [PDF]

open access: yes, 2013
Shape differences are manifested in cortical structures due to neuropsychiatric disorders. Such differences can be measured by labeled cortical distance mapping (LCDM) which characterizes the morphometry of the laminar cortical mantle of cortical ...
Alexopolous, J.   +6 more
core   +2 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Crossmodal Connections of Primary Sensory Cortices Largely Vanish During Normal Aging

open access: yesFrontiers in Aging Neuroscience, 2018
During aging, human response times (RTs) to unisensory and crossmodal stimuli decrease. However, the elderly benefit more from crossmodal stimulus representations than younger people.
Julia U. Henschke   +9 more
doaj   +1 more source

Fundamental activity constraints lead to specific interpretations of the connectome [PDF]

open access: yes, 2017
The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to experimental ...
Diesmann, Markus   +4 more
core   +4 more sources

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

A unified framework for the organisation of the primate auditory cortex

open access: yesFrontiers in Systems Neuroscience, 2013
In nonhuman primates a scheme for the organisation of the auditory cortex is frequently used to localise auditory processes. The scheme allows a common basis for comparison of functional organisation across nonhuman primate species.
Simon eBaumann   +2 more
doaj   +1 more source

The functional organization of area V2, I: Specialization across stripes and layers [PDF]

open access: yes, 2002
We used qualitative tests to assess the sensitivity of 1043 V2 neurons (predominantly multiunits) in anesthetised macaque monkeys to direction, length. orientation. and color of moving bar stimuli.
Shipp, S, Zeki, S
core   +1 more source

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