Results 1 to 10 of about 2,329,584 (350)

Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence

open access: yesJCI Insight, 2020
In aging mice, osteoclast number increases in cortical bone but declines in trabecular bone, suggesting that different mechanisms underlie age-associated bone loss in these 2 compartments.
Ha-Neui Kim   +13 more
doaj   +2 more sources

Predicting cortical bone adaptation to axial loading in the mouse tibia [PDF]

open access: yesJournal of the Royal Society Interface, 2015
The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces.
A. A. Pitsillides   +9 more
core   +4 more sources

Biomechanical Evaluation of Bone Quality Effect on Stresses at Bone-Implant Interface: A Finite Element Study [PDF]

open access: yesJournal of Applied and Computational Mechanics, 2021
The aim of this study is to evaluate the effect of the alveolar bone quality on von Mises stress at the bone-implant interface during occlusal loading. Four (3D) finite element models of fully osteointegrated 3-mm diameter × 11.5-mm length dental implant
Belaid TAHAROU   +7 more
doaj   +1 more source

Cortical bone density by quantitative computed tomography mirrors disorders of bone structure in bone biopsy of non-dialysis CKD patients

open access: yesBone Reports, 2022
Bone biopsy is still the gold standard tool to evaluate either trabecular or cortical bone, though the quantitative computed tomography of the vertebrae (QCT), a non-invasive technique, could be useful to evaluate bone structure in patients with chronic ...
Amandha L. Bittencourt   +4 more
doaj   +1 more source

Growth and Age-Related Abnormalities in Cortical Structure and Fracture Risk [PDF]

open access: yesEndocrinology and Metabolism, 2015
Vertebral fractures and trabecular bone loss have dominated thinking and research into the pathogenesis and the structural basis of bone fragility during the last 70 years.
Ego Seeman
doaj   +1 more source

Long‐Term Immobilization in Elderly Females Causes a Specific Pattern of Cortical Bone and Osteocyte Deterioration Different From Postmenopausal Osteoporosis

open access: yesJournal of Bone and Mineral Research, 2020
Immobilization as a result of long‐term bed rest can lead to gradual bone loss. Because of their distribution throughout the bone matrix and remarkable interconnectivity, osteocytes represent the major mechanosensors in bone and translate mechanical into
T. Rolvien   +10 more
semanticscholar   +1 more source

CBCT assessment of bone thickness in maxillary and mandibular teeth: an anatomic study [PDF]

open access: yesJournal of Applied Oral Science, 2020
The site of the sinus tract depends on the rate of resistance against abscess exudate drainage, bone morphology, and distance from the root apex to the outer cortical bone. Objective To assess apical bone thickness in buccal and palatal/lingual aspects
Olavo César Lyra PORTO   +6 more
doaj   +2 more sources

Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age [PDF]

open access: yes, 2018
Cortical bone is permeated by a system of pores, occupied by the blood supply and osteocytes. With ageing, bone mass reduction and disruption of the microstructure are associated with reduced vascular supply.
A Goring   +10 more
core   +9 more sources

Bone mineral density and mandibular osteoporotic alterations in panoramic radiographs: Correlation by peripheral bone densitometry in men

open access: yesIndian Journal of Dental Research, 2020
Aim: Mandibular cortical index has proven to be inversely correlated to bone densitometry; however, trabecular bone pattern has not been widely studied. Thus, the main objectives of this study were: (1) to analyze the correlations between three different
Luciana Munhoz   +4 more
doaj   +1 more source

Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes

open access: yeseLife, 2020
Bone strength is determined by its dense cortical shell, generated by unknown mechanisms. Here we use the Dmp1Cre:Socs3f/f mouse, with delayed cortical bone consolidation, to characterise cortical maturation and identify control signals.
Emma C Walker   +7 more
doaj   +1 more source

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