Results 211 to 220 of about 2,329,584 (350)

Altered Bone Mechanics, Architecture and Composition in the Skeleton of TIMP-3-Deficient Mice [PDF]

, 2017
A Bruni-Cardoso, A Carriero, A Carriero, A Carriero, A Janssen, A Ural, Adele Boskey, AL Boskey, AL Boskey, Alessandra Carriero, Andrew A. Pitsillides, B Javaheri, Behzad Javaheri, BH Weber, Brendyn Miller, CH Turner, D Stickens, E Donnelly, E Ohuchi, EL Martin, EP Paschalis, FF Mohammed, George Bou-Gharios, H Isaksson, H Zhao, HH Malluche, J Verstappen, K Bell, K Brew, K Holmbeck, K Verdelis, KJ Leco, L Hammoud, L Spevak, Lyudmila Lukashova, Lyudmila Spevak, M Federici, M Inada, M Marzia, ME Marisa, ML Bouxsein, P Garnero, PW Fedak, R Ritchie, R Shigdel, S Sahebjam, S Verrier, SE Gill, SS Apte, T Maretzky, W Cruz-Munoz, Y Shen   +51 more
core   +3 more sources

A new WNT on the bone: WNT16, cortical bone thickness, porosity and fractures.

BoneKEy Reports, 2015
F. Gori, U. Lerner, C. Ohlsson, R. Baron
semanticscholar   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Cortical bone porosity is spatially heterogeneous and VEGF dependent in male bone.

Dis Model Mech
Trend J, Keen J, Sharma A, Sharma A, Michels L, Goggin P, Schneider P, Deinhardt K, Clarkin CE.   +8 more
europepmc   +1 more source

Inter-implant distance correlated to different preparation protocol on cortical bone: an animal study. [PDF]

BMC Oral Health
Toia M, Stocchero M, Jinno Y, Herath M, Galli S, Papia E, Ahmad M, Becktor JP.   +7 more
europepmc   +1 more source

The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts

Journal of Bone and Mineral Research, 2015
Serra Ucer, Srividhya Iyer, S. M. Bartell, M. Martín-Millán, Li Han, Ha-Neui Kim, R. Weinstein, R. Jilka, C. O’Brien, Maria Almeida, S. Manolagas   +10 more
semanticscholar   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Estrogen signaling in PDGFRα+ cells positively regulates cortical bone metabolism via IGFBP5 in female mice. [PDF]

JBMR Plus
Ikedo A, Aoki R, Sakai H, Saeki N, Yanagihara Y, Moody J, Kojima M, Kouno T, Ando Y, Hino K, Kinoshita T, Carninci P, Shin JW, Hon CC, Uezumi A, Kamei Y, Imai Y.   +16 more
europepmc   +1 more source

Denosumab Rapidly Increases Cortical Bone in Key Locations of the Femur: A 3D Bone Mapping Study in Women With Osteoporosis

Journal of Bone and Mineral Research, 2015
K. Poole, Graham M. Treece, A. Gee, Jacques P. Brown, M. McClung, Andrea T Wang, C. Libanati   +6 more
semanticscholar   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source