Results 231 to 240 of about 2,329,584 (350)

Compromised cortical bone compartment in type 2 diabetes mellitus patients with microvascular disease.

European Journal of Endocrinology, 2015
V. Shanbhogue, S. Hansen, M. Frost, N. Jørgensen, A. Hermann, J. Henriksen, K. Brixen   +6 more
semanticscholar   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Fluorescent collagen hybridizing peptide for quantifying collagen denaturation in cortical bone. [PDF]

Bone Rep
Woolley W, Chin N, Yu SM, Acevedo C.
europepmc   +1 more source

Shear deformation and fracture of human cortical bone.

Bone, 2015
Tengteng Tang, Vincent Ebacher, P. Cripton, P. Guy, H. McKay, Rizhi Wang   +5 more
semanticscholar   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

In C57BL/6J mice, weight loss in previously obese mice reduced bone mass and shifted the cortical bone metabolome. [PDF]

Bone
Chlebek C, McAndrews C, Aaronson B, Welhaven HD, Yu K, Costa SN, Shaver J, Silvia S, DeMambro VE, June RK, McGee-Lawrence ME, Rosen CJ.   +11 more
europepmc   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Is Mandibular Cortical Bone and Trabecular Microarchitecture Altered by Masseter Botox Treatment? A Quantitative Perspective. [PDF]

Diagnostics (Basel)
Yuksel IB, Altiparmak F, Bahrilli S, Ucan Yarkac F, Sen DO, Orhan K.   +5 more
europepmc   +1 more source

Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs

Journal of Bone and Mineral Research, 2016
Pamela Cabahug-Zuckerman, Dorra Frikha‐Benayed, R. Majeska, Alyssa Tuthill, S. Yakar, S. Judex, M. Schaffler   +6 more
semanticscholar   +1 more source

A smart headband for multimodal physiological monitoring in human exercises

Advanced Science, EarlyView.
A novel smart headband incorporating a thermal‐sensation‐based electronic skin is presented for continuous and accurate multimodal physiological monitoring, including pulse waveforms, total metabolic energy expenditure, heart rate, and forehead temperature, across both static and dynamic daily activities.
Shiqiang Liu, Guanxing Chen, Jingyi Peng, Shuo Tian, Qian Mao, Caise Wei, Jinfeng Yuan, Rong Zhu   +7 more
wiley   +1 more source